Detalles de la búsqueda
1.
In Vitro Testing of Sunscreens for Dermal Absorption: Method Comparison and Rank Order Correlation with In Vivo Absorption.
AAPS PharmSciTech
; 23(5): 121, 2022 Apr 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-35459978
2.
Effect of Oral Ranitidine on Urinary Excretion of N-Nitrosodimethylamine (NDMA): A Randomized Clinical Trial.
JAMA
; 326(3): 240-249, 2021 07 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-34180947
3.
Effect of Sunscreen Application on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial.
JAMA
; 323(3): 256-267, 2020 01 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-31961417
4.
Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial.
JAMA
; 321(21): 2082-2091, 2019 06 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-31058986
5.
A Bioanalytical Method for Quantification of N-nitrosodimethylamine (NDMA) in Human Plasma and Urine with Different Meals and following Administration of Ranitidine.
J Pharm Sci
; 112(5): 1315-1323, 2023 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36736776
6.
Considerations for Use of Pharmacodynamic Biomarkers to Support Biosimilar Development - (I) A Randomized Trial with PCSK9 Inhibitors.
Clin Pharmacol Ther
; 113(1): 71-79, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36282186
7.
Considerations for Use of Pharmacodynamic Biomarkers to Support Biosimilar Development - (II) A Randomized Trial with IL-5 Antagonists.
Clin Pharmacol Ther
; 113(1): 80-89, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36184697
8.
Considerations for Use of Pharmacodynamic Biomarkers to Support Biosimilar Development - (III) A Randomized Trial with Interferon Beta-1a Products.
Clin Pharmacol Ther
; 113(2): 339-348, 2023 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-36324229
9.
Evaluating the Utility of Proteomics for the Identification of Circulating Pharmacodynamic Biomarkers of IFNß-1a Biologics.
Clin Pharmacol Ther
; 113(1): 98-107, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36308070
10.
hERG block potencies for 5 positive control drugs obtained per ICH E14/S7B Q&As best practices: Impact of recording temperature and drug loss.
J Pharmacol Toxicol Methods
; 117: 107193, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35792285
11.
Determination of five positive control drugs in hERG external solution (buffer) by LC-MS/MS to support in vitro hERG assay as recommended by ICH S7B.
J Pharmacol Toxicol Methods
; 118: 107229, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36334898
12.
New science, drug regulation, and emergent public health issues: The work of FDA's division of applied regulatory science.
Front Med (Lausanne)
; 9: 1109541, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36743666
13.
Novel simultaneous method for the determination of avobenzone and oxybenzone in human plasma by UHPLC-MS/MS with phospholipid removal pretreatment: An application to a sunscreen clinical trial.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1169: 122615, 2021 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33706185
14.
Characterizing the reproducibility in using a liver microphysiological system for assaying drug toxicity, metabolism, and accumulation.
Clin Transl Sci
; 14(3): 1049-1061, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33382907
15.
Effects of sedative psychotropic drugs combined with oxycodone on respiratory depression in the rat.
Clin Transl Sci
; 14(6): 2208-2219, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34080766
16.
Novel High-Throughput Quantitation of Potent hERG Blocker Dofetilide in Human Plasma by Liquid Chromatography Tandem Mass Spectrometry: Application in a Phase 1 ECG Biomarker Validation Study.
J Anal Toxicol
; 44(2): 180-187, 2020 Mar 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-31355881
17.
A high-throughput bioanalytical assay to support pharmacokinetic interaction study of oxycodone and diazepam in Sprague Dawley rats.
RSC Adv
; 10(2): 886-896, 2020 Jan 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-35494453
18.
Quantitative analysis of underivatized 17 ß-estradiol using a high-throughput LC-MS/MS assay - Application to support a pharmacokinetic study in ovariectomized guinea pigs.
J Pharm Biomed Anal
; 178: 112897, 2020 Jan 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-31593865
19.
Developing an animal model to detect drug-drug interactions impacting drug-induced respiratory depression.
Toxicol Rep
; 7: 188-197, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32021808
20.
Simultaneous UHPLC-MS/MS method of estradiol metabolites to support the evaluation of Phase-2 metabolic activity of induced pluripotent stem cell derived hepatocytes.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1126-1127: 121765, 2019 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31434025