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1.
The bacterial iron sensor IdeR recognizes its DNA targets by indirect readout.
Nucleic Acids Res
; 49(17): 10120-10135, 2021 09 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-34417623
2.
ß-Ureidopropionase deficiency due to novel and rare UPB1 mutations affecting pre-mRNA splicing and protein structural integrity and catalytic activity.
Mol Genet Metab
; 136(3): 177-185, 2022 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35151535
3.
Crystal structure and pH-dependent allosteric regulation of human ß-ureidopropionase, an enzyme involved in anticancer drug metabolism.
Biochem J
; 475(14): 2395-2416, 2018 07 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-29976570
4.
Genome sequencing reveals a novel genetic mechanism underlying dihydropyrimidine dehydrogenase deficiency: A novel missense variant c.1700G>A and a large intragenic inversion in DPYD spanning intron 8 to intron 12.
Hum Mutat
; 39(7): 947-953, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29691939
5.
Directed Evolution of Alcohol Dehydrogenase for Improved Stereoselective Redox Transformations of 1-Phenylethane-1,2-diol and Its Corresponding Acyloin.
Biochemistry
; 57(7): 1059-1062, 2018 02 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-29384657
6.
Severe fluoropyrimidine toxicity due to novel and rare DPYD missense mutations, deletion and genomic amplification affecting DPD activity and mRNA splicing.
Biochim Biophys Acta Mol Basis Dis
; 1863(3): 721-730, 2017 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-28024938
7.
Relaxation of nonproductive binding and increased rate of coenzyme release in an alcohol dehydrogenase increases turnover with a nonpreferred alcohol enantiomer.
FEBS J
; 284(22): 3895-3914, 2017 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-28963762
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