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1.
Micro-CT imaging of tumor angiogenesis: quantitative measures describing micromorphology and vascularization.
Am J Pathol
; 184(2): 431-41, 2014 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-24262753
2.
A longitudinal study assessing lens thickness changes in the eye of the growing beagle using ultrasound scanning: relevance to age of dogs in regulatory toxicology studies.
J Appl Toxicol
; 34(12): 1368-72, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-24436247
3.
The Opportunities and Use of Imaging to Measure Target Engagement.
SLAS Discov
; 25(2): 127-136, 2020 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31885303
4.
High-resolution 3D visualization of nanomedicine distribution in tumors.
Theranostics
; 10(2): 880-897, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-31903157
5.
Ultrasound-triggered therapeutic microbubbles enhance the efficacy of cytotoxic drugs by increasing circulation and tumor drug accumulation and limiting bioavailability and toxicity in normal tissues.
Theranostics
; 10(24): 10973-10992, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-33042265
6.
Combined Inhibition of PI3Kß and mTOR Inhibits Growth of PTEN-null Tumors.
Mol Cancer Ther
; 17(11): 2309-2319, 2018 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-30097489
7.
The use of 18F-Fluoro-deoxy-glucose positron emission tomography (18F-FDG PET) as a non-invasive pharmacodynamic biomarker to determine the minimally pharmacologically active dose of AZD8835, a novel PI3Kα inhibitor.
PLoS One
; 12(8): e0183048, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28806782
8.
The use of (18)F-fluorodeoxyglucose positron emission tomography ((18)F-FDG PET) as a pathway-specific biomarker with AZD8186, a PI3Kß/δ inhibitor.
EJNMMI Res
; 6(1): 62, 2016 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-27515445
9.
Examining changes in [18 F]FDG and [18 F]FLT uptake in U87-MG glioma xenografts as early response biomarkers to treatment with the dual mTOR1/2 inhibitor AZD8055.
Mol Imaging Biol
; 16(3): 421-30, 2014 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-24249640
10.
2-Deoxy-2-[18F]fluoro-D-glucose positron emission tomography demonstrates target inhibition with the potential to predict anti-tumour activity following treatment with the AKT inhibitor AZD5363.
Mol Imaging Biol
; 15(4): 476-85, 2013 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-23344784
11.
Preclinical pharmacology of AZD5363, an inhibitor of AKT: pharmacodynamics, antitumor activity, and correlation of monotherapy activity with genetic background.
Mol Cancer Ther
; 11(4): 873-87, 2012 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-22294718
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