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1.
Design and synthesis of tetrahydropyridopyrimidine based Toll-Like Receptor (TLR) 7/8 dual agonists.
Bioorg Med Chem Lett
; 28(19): 3216-3221, 2018 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30143425
2.
Synthesis and evaluation of novel HCV replication inhibitors.
Mol Divers
; 21(2): 475-481, 2017 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-28293834
3.
Latest Advances in Small Molecule TLR 7/8 Agonist Drug Research.
Curr Top Med Chem
; 19(24): 2228-2238, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31769363
4.
Design, Synthesis, and Biological Evaluation of Novel Indoles Targeting the Influenza PB2 Cap Binding Region.
J Med Chem
; 62(21): 9680-9690, 2019 11 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-31647875
5.
Structure-guided design of aminopyrimidine amides as potent, selective inhibitors of lymphocyte specific kinase: synthesis, structure-activity relationships, and inhibition of in vivo T cell activation.
J Med Chem
; 51(6): 1681-94, 2008 Mar 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-18321037
6.
Identification and Optimization of Pyrrolo[3,2-d]pyrimidine Toll-like Receptor 7 (TLR7) Selective Agonists for the Treatment of Hepatitis B.
J Med Chem
; 60(14): 6137-6151, 2017 07 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-28671847
7.
Novel 2-aminopyrimidine carbamates as potent and orally active inhibitors of Lck: synthesis, SAR, and in vivo antiinflammatory activity.
J Med Chem
; 49(16): 4981-91, 2006 Aug 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-16884310
8.
Discovery of aminoquinazolines as potent, orally bioavailable inhibitors of Lck: synthesis, SAR, and in vivo anti-inflammatory activity.
J Med Chem
; 49(19): 5671-86, 2006 Sep 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-16970394
9.
Versatile Multicomponent Reaction Macrocycle Synthesis Using α-Isocyano-ω-carboxylic Acids.
Org Lett
; 17(20): 4980-3, 2015 Oct 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-26439710
10.
Discovery of novel 2,3-diarylfuro[2,3-b]pyridin-4-amines as potent and selective inhibitors of Lck: synthesis, SAR, and pharmacokinetic properties.
Bioorg Med Chem Lett
; 17(8): 2299-304, 2007 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17276681
11.
Discovery of 4-amino-5,6-biaryl-furo[2,3-d]pyrimidines as inhibitors of Lck: development of an expedient and divergent synthetic route and preliminary SAR.
Bioorg Med Chem Lett
; 17(8): 2305-9, 2007 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17280833
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