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1.
From scarcity to solutions: Therapeutic strategies to restore adipose tissue functionality in rare disorders of lipodystrophy.
Diabet Med
; 40(12): e15214, 2023 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37638531
2.
High-fat diet exacerbates cognitive and metabolic abnormalities in neuronal BACE1 knock-in mice - partial prevention by Fenretinide.
Nutr Neurosci
; 25(4): 719-736, 2022 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-32862802
3.
GLP-1 receptor agonist improves metabolic disease in a pre-clinical model of lipodystrophy.
Front Endocrinol (Lausanne)
; 15: 1379228, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38745956
4.
Proceedings of the annual meeting of the European Consortium of Lipodystrophies (ECLip), Pisa, Italy, 28-29 September 2023.
Ann Endocrinol (Paris)
; 2024 Mar 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38452868
5.
Expression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independently of dietary restriction.
Proc Natl Acad Sci U S A
; 107(20): 9105-10, 2010 May 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-20435911
6.
Gene therapy restores adipose tissue and metabolic health in a pre-clinical mouse model of lipodystrophy.
Mol Ther Methods Clin Dev
; 27: 206-216, 2022 Dec 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-36320417
7.
Bscl2 Deficiency Does Not Directly Impair the Innate Immune Response in a Murine Model of Generalized Lipodystrophy.
J Clin Med
; 10(3)2021 Jan 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-33498782
8.
Production of reactive oxygen species by the mitochondrial electron transport chain in Drosophila melanogaster.
J Bioenerg Biomembr
; 42(2): 135-42, 2010 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-20300811
9.
Ablation of Bscl2/seipin in hepatocytes does not cause metabolic dysfunction in congenital generalised lipodystrophy.
Dis Model Mech
; 13(1)2020 01 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-31848133
10.
Oligomers of the lipodystrophy protein seipin may co-ordinate GPAT3 and AGPAT2 enzymes to facilitate adipocyte differentiation.
Sci Rep
; 10(1): 3259, 2020 02 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-32094408
11.
Female adipose tissue-specific Bscl2 knockout mice develop only moderate metabolic dysfunction when housed at thermoneutrality and fed a high-fat diet.
Sci Rep
; 8(1): 17863, 2018 12 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-30552349
12.
Adipose specific disruption of seipin causes early-onset generalised lipodystrophy and altered fuel utilisation without severe metabolic disease.
Mol Metab
; 10: 55-65, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29459250
13.
Elevated Fibroblast growth factor 21 (FGF21) in obese, insulin resistant states is normalised by the synthetic retinoid Fenretinide in mice.
Sci Rep
; 7: 43782, 2017 03 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-28256636
14.
Fenretinide mediated retinoic acid receptor signalling and inhibition of ceramide biosynthesis regulates adipogenesis, lipid accumulation, mitochondrial function and nutrient stress signalling in adipocytes and adipose tissue.
Biochem Pharmacol
; 100: 86-97, 2016 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26592777
15.
Fenretinide prevents obesity in aged female mice in association with increased retinoid and estrogen signaling.
Obesity (Silver Spring)
; 23(8): 1655-62, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-26179846
16.
The mechanisms of Fenretinide-mediated anti-cancer activity and prevention of obesity and type-2 diabetes.
Biochem Pharmacol
; 91(3): 277-86, 2014 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25069047
17.
Fenretinide treatment prevents diet-induced obesity in association with major alterations in retinoid homeostatic gene expression in adipose, liver, and hypothalamus.
Diabetes
; 62(3): 825-36, 2013 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-23193184
18.
Adipocyte-specific protein tyrosine phosphatase 1B deletion increases lipogenesis, adipocyte cell size and is a minor regulator of glucose homeostasis.
PLoS One
; 7(2): e32700, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22389718
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