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1.
ERK Inhibitor LY3214996 Targets ERK Pathway-Driven Cancers: A Therapeutic Approach Toward Precision Medicine.
Mol Cancer Ther
; 19(2): 325-336, 2020 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31744895
2.
Optimization of a dihydropyrrolopyrazole series of transforming growth factor-beta type I receptor kinase domain inhibitors: discovery of an orally bioavailable transforming growth factor-beta receptor type I inhibitor as antitumor agent.
J Med Chem
; 51(7): 2302-6, 2008 Apr 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-18314943
3.
Preclinical assessment of galunisertib (LY2157299 monohydrate), a first-in-class transforming growth factor-ß receptor type I inhibitor.
Oncotarget
; 9(6): 6659-6677, 2018 Jan 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-29467918
4.
Merging two universities: the Medical University of Ohio and the University of Toledo.
Acad Med
; 82(12): 1187-95, 2007 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-18046124
5.
Dihydropyrrolopyrazole transforming growth factor-beta type I receptor kinase domain inhibitors: a novel benzimidazole series with selectivity versus transforming growth factor-beta type II receptor kinase and mixed lineage kinase-7.
J Med Chem
; 49(6): 2138-42, 2006 Mar 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-16539403
6.
"On demand" sedation for colonoscopy with or without auricular acupuncture is non-inferior and may improve quality metrics compared to "upfront" sedation.
Dig Liver Dis
; 53(5): 669-671, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33737006
7.
Synthesis and activity of new aryl- and heteroaryl-substituted pyrazole inhibitors of the transforming growth factor-beta type I receptor kinase domain.
J Med Chem
; 46(19): 3953-6, 2003 Sep 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-12954047
8.
Synthesis and antibacterial activity of C11, C12-cyclic urea analogues of ketolides.
Bioorg Med Chem Lett
; 17(18): 5013-8, 2007 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17692517
9.
Kinetic characterization of novel pyrazole TGF-beta receptor I kinase inhibitors and their blockade of the epithelial-mesenchymal transition.
Biochemistry
; 44(7): 2293-304, 2005 Feb 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-15709742
10.
Synthesis and activity of new aryl- and heteroaryl-substituted 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole inhibitors of the transforming growth factor-beta type I receptor kinase domain.
Bioorg Med Chem Lett
; 14(13): 3581-4, 2004 Jul 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-15177479
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