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1.
Synthesis and structure-activity relationships of imidazo[1,2-a]pyrimidin-5(1H)-ones as a novel series of beta isoform selective phosphatidylinositol 3-kinase inhibitors.
Bioorg Med Chem Lett
; 22(6): 2230-4, 2012 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22361133
2.
Synthesis and structure-activity relationships of 1,2,4-triazolo[1,5-a]pyrimidin-7(3H)-ones as novel series of potent ß isoform selective phosphatidylinositol 3-kinase inhibitors.
Bioorg Med Chem Lett
; 22(9): 3198-202, 2012 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22475557
3.
Differences in effects on myocardium and mitochondria by angiogenic inhibitors suggest separate mechanisms of cardiotoxicity.
Toxicol Pathol
; 38(5): 691-702, 2010 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-20616376
4.
Preclinical drug metabolism and pharmacokinetic evaluation of GW844520, a novel anti-malarial mitochondrial electron transport inhibitor.
J Pharm Sci
; 95(12): 2657-72, 2006 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-16892205
5.
[3a,4]-Dihydropyrazolo[1,5a]pyrimidines: Novel, Potent, and Selective Phosphatidylinositol-3-kinase ß Inhibitors.
ACS Med Chem Lett
; 4(2): 230-4, 2013 Feb 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-24900655
6.
Quinoline 3-sulfonamides inhibit lactate dehydrogenase A and reverse aerobic glycolysis in cancer cells.
Cancer Metab
; 1(1): 19, 2013 Sep 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-24280423
7.
Rational Design, Synthesis, and SAR of a Novel Thiazolopyrimidinone Series of Selective PI3K-beta Inhibitors.
ACS Med Chem Lett
; 3(7): 524-9, 2012 Jul 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-24900504
8.
Development of an in vivo preclinical screen model to estimate absorption and first-pass hepatic extraction of xenobiotics. II. Use of ketoconazole to identify P-glycoprotein/CYP3A-limited bioavailability in the monkey.
Drug Metab Dispos
; 32(2): 172-7, 2004 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-14744938
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