Detalles de la búsqueda
1.
The UDP-Glycosyltransferase (UGT) Superfamily: New Members, New Functions, and Novel Paradigms.
Physiol Rev
; 99(2): 1153-1222, 2019 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30724669
2.
The molecular basis of dapsone activation of CYP2C9-catalyzed nonsteroidal anti-inflammatory drug oxidation.
J Biol Chem
; 299(12): 105368, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37866634
3.
Activation of Cryptic Donor Splice Sites within the UDP-Glucuronosyltransferase (UGT)1A First-Exon Region Generates Variant Transcripts That Encode UGT1A Proteins with Truncated Aglycone-Binding Domains.
Drug Metab Dispos
; 52(6): 526-538, 2024 May 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-38565302
4.
A lack of association between BMI and chemoimmunotherapy efficacy in advanced non-small cell lung cancer: Secondary analysis of the IMpower150 and IMpower130 clinical trials.
BMC Cancer
; 24(1): 379, 2024 Mar 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-38528478
5.
A 10-year update to the principles for clinical trial data sharing by pharmaceutical companies: perspectives based on a decade of literature and policies.
BMC Med
; 21(1): 400, 2023 10 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-37872545
6.
Binding of SEP-363856 within TAAR1 and the 5HT1A receptor: implications for the design of novel antipsychotic drugs.
Mol Psychiatry
; 27(1): 88-94, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34376825
7.
Efficacy of first-line atezolizumab combination therapy in patients with non-small cell lung cancer receiving proton pump inhibitors: post hoc analysis of IMpower150.
Br J Cancer
; 126(1): 42-47, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34711947
8.
Regulation of human UDP-glycosyltransferase (UGT) genes by miRNAs.
Drug Metab Rev
; 54(2): 120-140, 2022 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35275773
9.
Chemical similarities and differences among inhibitors of nitric oxide synthase, arginase and dimethylarginine dimethylaminohydrolase-1: Implications for the design of novel enzyme inhibitors modulating the nitric oxide pathway.
Bioorg Med Chem
; 72: 116970, 2022 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36063653
10.
Circular RNAs of UDP-Glycosyltransferase (UGT) Genes Expand the Complexity and Diversity of the UGT Transcriptome.
Mol Pharmacol
; 99(6): 488-503, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33824186
11.
Binding of clozapine to the GABAB receptor: clinical and structural insights.
Mol Psychiatry
; 25(9): 1910-1919, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32203158
12.
Evaluation of the prescribing practice of guideline-directed medical therapy among ambulatory chronic heart failure patients.
BMC Cardiovasc Disord
; 21(1): 104, 2021 02 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-33602125
13.
Arginine-259 of UGT2B7 Confers UDP-Sugar Selectivity.
Mol Pharmacol
; 98(6): 710-718, 2020 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33008919
14.
Effect of early adverse events resulting in ado-trastuzumab emtansine dose adjustments on survival outcomes of HER2+ advanced breast cancer patients.
Breast Cancer Res Treat
; 178(2): 473-477, 2019 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-31399933
15.
Deregulation of the Genes that Are Involved in Drug Absorption, Distribution, Metabolism, and Excretion in Hepatocellular Carcinoma.
J Pharmacol Exp Ther
; 368(3): 363-381, 2019 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-30578287
16.
Effectiveness of the Pharmacist-Involved Multidisciplinary Management of Heart Failure to Improve Hospitalizations and Mortality Rates in 4630 Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
J Card Fail
; 25(9): 744-756, 2019 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-31351119
17.
Computational Prediction of the Site(s) of Metabolism and Binding Modes of Protein Kinase Inhibitors Metabolized by CYP3A4.
Drug Metab Dispos
; 47(6): 616-631, 2019 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-30902802
18.
Cooperative Regulation of Intestinal UDP-Glucuronosyltransferases 1A8, -1A9, and 1A10 by CDX2 and HNF4α Is Mediated by a Novel Composite Regulatory Element.
Mol Pharmacol
; 93(5): 541-552, 2018 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29519853
19.
Intergenic Splicing between Four Adjacent UGT Genes (2B15, 2B29P2, 2B17, 2B29P1) Gives Rise to Variant UGT Proteins That Inhibit Glucuronidation via Protein-Protein Interactions.
Mol Pharmacol
; 94(3): 938-952, 2018 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-29959221
20.
Regulation of UDP-Glucuronosyltransferase 2B15 by miR-331-5p in Prostate Cancer Cells Involves Canonical and Noncanonical Target Sites.
J Pharmacol Exp Ther
; 365(1): 48-59, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29367276