Detalles de la búsqueda
1.
Structural features underlying the selectivity of the kinase inhibitors NBC and dNBC: role of a nitro group that discriminates between CK2 and DYRK1A.
Cell Mol Life Sci
; 69(3): 449-60, 2012 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-21720886
2.
Inhibition of protein kinase CK2 by flavonoids and tyrphostins. A structural insight.
Biochemistry
; 51(31): 6097-107, 2012 Aug 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-22794353
3.
Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical trials for the treatment of cancer.
Biochemistry
; 50(39): 8478-88, 2011 Oct 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-21870818
4.
Cystic fibrosis transmembrane regulator fragments with the Phe508 deletion exert a dual allosteric control over the master kinase CK2.
Biochem J
; 426(1): 19-29, 2010 Jan 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-19925455
5.
Pancreatic and duodenal homeobox 1 (PDX1) phosphorylation at serine-269 is HIPK2-dependent and affects PDX1 subnuclear localization.
Biochem Biophys Res Commun
; 399(2): 155-61, 2010 Aug 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-20637728
6.
The pleiotropic protein kinase CK2 phosphorylates HTLV-1 Tax protein in vitro, targeting its PDZ-binding motif.
Virus Genes
; 41(2): 149-57, 2010 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-20526659
7.
Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2.
Biochem J
; 421(3): 387-95, 2009 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19432557
8.
A modified KESTREL search reveals a basophilic substrate consensus for the Saccharomyces cerevisiae Npr1 protein kinase.
J Proteome Res
; 8(11): 5305-16, 2009 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-19780626
9.
Tetraiodobenzimidazoles are potent inhibitors of protein kinase CK2.
Bioorg Med Chem
; 17(20): 7281-9, 2009 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19748274
10.
The selectivity of inhibitors of protein kinase CK2: an update.
Biochem J
; 415(3): 353-65, 2008 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18588507
11.
Modulation of protein kinase CK2 activity by fragments of CFTR encompassing F508 may reflect functional links with cystic fibrosis pathogenesis.
Biochemistry
; 47(30): 7925-36, 2008 Jul 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-18597485
12.
The regulatory beta subunit of protein kinase CK2 contributes to the recognition of the substrate consensus sequence. A study with an eIF2 beta-derived peptide.
Biochemistry
; 47(32): 8317-25, 2008 Aug 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-18636746
13.
Coumarin as attractive casein kinase 2 (CK2) inhibitor scaffold: an integrate approach to elucidate the putative binding motif and explain structure-activity relationships.
J Med Chem
; 51(4): 752-9, 2008 Feb 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-18251491
14.
Identification of novel protein kinase CK1 delta (CK1delta) inhibitors through structure-based virtual screening.
Bioorg Med Chem Lett
; 18(20): 5672-5, 2008 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18799313
15.
Discrimination between the activity of protein kinase CK2 holoenzyme and its catalytic subunits.
FEBS Lett
; 580(16): 3948-52, 2006 Jul 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-16806200
16.
Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application.
J Med Chem
; 49(8): 2363-6, 2006 Apr 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-16610779
17.
Aurora-A site specificity: a study with synthetic peptide substrates.
Biochem J
; 390(Pt 1): 293-302, 2005 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-16083426
18.
Generation of protein kinase Ck1alpha mutants which discriminate between canonical and non-canonical substrates.
Biochem J
; 391(Pt 2): 417-24, 2005 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-15975091
19.
CK2-dependent phosphorylation of the E2 ubiquitin conjugating enzyme UBC3B induces its interaction with beta-TrCP and enhances beta-catenin degradation.
Oncogene
; 21(25): 3978-87, 2002 Jun 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-12037680
20.
Toward the rational design of protein kinase casein kinase-2 inhibitors.
Pharmacol Ther
; 93(2-3): 159-68, 2002.
Artículo
en Inglés
| MEDLINE | ID: mdl-12191608