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1.
Alkylating histone deacetylase inhibitors may have therapeutic value in experimental myeloperoxidase-ANCA vasculitis.
Kidney Int
; 94(5): 926-936, 2018 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-30158055
2.
Detection and outcome of occult leptomeningeal disease in diffuse large B-cell lymphoma and Burkitt lymphoma.
Haematologica
; 99(7): 1228-35, 2014 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-24727817
3.
Purine nucleoside phosphorylase enables dual metabolic checkpoints that prevent T cell immunodeficiency and TLR7-associated autoimmunity.
J Clin Invest
; 132(16)2022 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-35653193
4.
Forodesine has high antitumor activity in chronic lymphocytic leukemia and activates p53-independent mitochondrial apoptosis by induction of p73 and BIM.
Blood
; 114(8): 1563-75, 2009 Aug 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-19541822
5.
Chemotherapy is getting 'smarter'.
Future Oncol
; 11(4): 549-52, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25686110
6.
Challenges in Optimising the Successful Construction of Antibody Drug Conjugates in Cancer Therapy.
Antibodies (Basel)
; 7(1)2018 Feb 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-31544863
7.
Correction: Mehrling, T.; et al. Challenges in Optimising the Successful Construction of Antibody Drug Conjugates in Cancer Therapy. Antibodies 2018, 7, 11.
Antibodies (Basel)
; 7(3)2018 Aug 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-31544883
8.
Combined alkylation and histone deacetylase inhibition with EDO-S101 has significant therapeutic activity against brain tumors in preclinical models.
Oncotarget
; 9(46): 28155-28164, 2018 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29963268
9.
Strategy for Assessing New Drug Value in Orphan Diseases: An International Case Match Control Analysis of the PROPEL Study.
JNCI Cancer Spectr
; 2(4): pky038, 2018 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-31360868
10.
The first-in-class alkylating deacetylase inhibitor molecule tinostamustine shows antitumor effects and is synergistic with radiotherapy in preclinical models of glioblastoma.
J Hematol Oncol
; 11(1): 32, 2018 02 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-29486795
11.
Establishment and Characterization of a Reliable Xenograft Model of Hodgkin Lymphoma Suitable for the Study of Tumor Origin and the Design of New Therapies.
Cancers (Basel)
; 10(11)2018 Oct 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-30384446
12.
Preclinical anti-myeloma activity of EDO-S101, a new bendamustine-derived molecule with added HDACi activity, through potent DNA damage induction and impairment of DNA repair.
J Hematol Oncol
; 10(1): 127, 2017 06 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-28633670
13.
The Alkylating-HDAC Inhibition Fusion Principle: Taking Chemotherapy to the Next Level with the First in Class Molecule EDO-S101.
Anticancer Agents Med Chem
; 16(1): 20-8, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-25980817
14.
Is there hope to treat glioblastoma effectively?
CNS Oncol
; 4(6): 377-9, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26507499
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