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1.
Comparison of AMG 416 and cinacalcet in rodent models of uremia.
BMC Nephrol
; 15: 81, 2014 May 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-24884838
2.
Pharmacology of AMG 416 (Velcalcetide), a novel peptide agonist of the calcium-sensing receptor, for the treatment of secondary hyperparathyroidism in hemodialysis patients.
J Pharmacol Exp Ther
; 346(2): 229-40, 2013 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-23674604
3.
CHIR-258 is efficacious in a newly developed fibroblast growth factor receptor 3-expressing orthotopic multiple myeloma model in mice.
Clin Cancer Res
; 12(16): 4908-15, 2006 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-16914579
4.
Contribution of individual targets to the antitumor efficacy of the multitargeted receptor tyrosine kinase inhibitor SU11248.
Mol Cancer Ther
; 5(5): 1280-9, 2006 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-16731761
5.
SU14813: a novel multiple receptor tyrosine kinase inhibitor with potent antiangiogenic and antitumor activity.
Mol Cancer Ther
; 5(7): 1774-82, 2006 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-16891463
6.
A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivo.
Cancer Res
; 63(21): 7345-55, 2003 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-14612533
7.
SU6668 inhibits Flk-1/KDR and PDGFRbeta in vivo, resulting in rapid apoptosis of tumor vasculature and tumor regression in mice.
FASEB J
; 16(7): 681-90, 2002 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-11978732
8.
Phase I dose-escalating study of SU11654, a small molecule receptor tyrosine kinase inhibitor, in dogs with spontaneous malignancies.
Clin Cancer Res
; 9(7): 2755-68, 2003 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-12855656
9.
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship.
Clin Cancer Res
; 9(1): 327-37, 2003 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-12538485
10.
Src family kinase activity is required for signal tranducer and activator of transcription 3 and focal adhesion kinase phosphorylation and vascular endothelial growth factor signaling in vivo and for anchorage-dependent and -independent growth of human tumor cells.
Mol Cancer Ther
; 2(5): 461-9, 2003 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-12748308
11.
CCR 20th Anniversary Commentary: Determining a Pharmacokinetic/Pharmacodynamic Relationship for SunitinibA Look Back.
Clin Cancer Res
; 21(11): 2415-7, 2015 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26034217
12.
Translational sciences approach to RSV vaccine development.
Expert Rev Vaccines
; 12(9): 1047-60, 2013 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-24053398
13.
Novel robust hepatitis C virus mouse efficacy model.
Antimicrob Agents Chemother
; 50(10): 3260-8, 2006 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-17005803
14.
Mechanism by which mutations at his274 alter sensitivity of influenza a virus n1 neuraminidase to oseltamivir carboxylate and zanamivir.
Antimicrob Agents Chemother
; 46(12): 3809-16, 2002 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-12435681
15.
Cytotoxicity of antiviral nucleotides adefovir and cidofovir is induced by the expression of human renal organic anion transporter 1.
J Am Soc Nephrol
; 11(3): 383-393, 2000 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-10703662
16.
Hair depigmentation is a biological readout for pharmacological inhibition of KIT in mice and humans.
J Pharmacol Exp Ther
; 307(2): 476-80, 2003 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-12966161
17.
Inhibition of constitutively active forms of mutant kit by multitargeted indolinone tyrosine kinase inhibitors.
Blood
; 100(2): 585-93, 2002 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-12091352
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