Detalles de la búsqueda
1.
Novel Proline Transporter Inhibitor (LQFM215) Presents Antipsychotic Effect in Ketamine Model of Schizophrenia.
Neurochem Res
; 49(1): 170-183, 2024 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-37684384
2.
Anti-inflammatory, antinociceptive, and vasorelaxant effects of a new pyrazole compound 5-(1-(2-fluorophenyl)-1H-pyrazol-4-yl)-1H-tetrazole: role of NO/cGMP pathway and calcium channels.
Can J Physiol Pharmacol
; 101(5): 216-225, 2023 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36866837
3.
LQFM289: Electrochemical and Computational Studies of a New Trimetozine Analogue for Anxiety Treatment.
Int J Mol Sci
; 24(19)2023 Sep 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-37834027
4.
Pharmacological evaluation of antinociceptive and anti-inflammatory activities of LQFM202: a new piperazine derivative.
Inflammopharmacology
; 31(1): 411-422, 2023 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-36443517
5.
Anti-inflammatory and antinociceptive effects, and safety toxicological profile of a new paracetamol analog, LQFM291.
Inflammopharmacology
; 31(5): 2451-2465, 2023 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-37667090
6.
Structure-activity relationship of three new piperazine derivates with anxiolytic-like and antidepressant-like effects.
Can J Physiol Pharmacol
; 100(6): 521-533, 2022 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35395172
7.
Mechanisms involved in the antinociceptive and anti-inflammatory effects of a new triazole derivative: 5-[1-(4-fluorophenyl)-1H-1,2,3-triazol-4-yl]-1H-tetrazole (LQFM-096).
Inflammopharmacology
; 28(4): 877-892, 2020 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-32030603
8.
Design, synthesis and pharmacological assessment of new pyrazole compounds.
Inflammopharmacology
; 28(4): 915-928, 2020 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-32529601
9.
Anti-inflammatory effect of a new piperazine derivative: (4-methylpiperazin-1-yl)(1-phenyl-1H-pyrazol-4-yl)methanone.
Inflammopharmacology
; 26(1): 217-226, 2018 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-28825161
10.
Molecular docking and pharmacological/toxicological assessment of a new compound designed from celecoxib and paracetamol by molecular hybridization.
Inflammopharmacology
; 26(5): 1189-1206, 2018 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-30039481
11.
Potential anti-inflammatory effect of LQFM-021 in carrageenan-induced inflammation: The role of nitric oxide.
Nitric Oxide
; 69: 35-44, 2017 Sep 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-28412475
12.
One step N-glycosylation by filamentous fungi biofilm in bioreactor of a new phosphodiesterase-3 inhibitor tetrazole.
Bioorg Med Chem Lett
; 26(13): 3177-3181, 2016 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27209234
13.
Pharmacological and toxicological evaluations of the new pyrazole compound (LQFM-021) as potential analgesic and anti-inflammatory agents.
Inflammopharmacology
; 24(5): 265-275, 2016 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-27671330
14.
Involvement of the NO/cGMP/KATP pathway in the antinociceptive effect of the new pyrazole 5-(1-(3-fluorophenyl)-1H-pyrazol-4-yl)-2H-tetrazole (LQFM-021).
Nitric Oxide
; 47: 17-24, 2015 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25754796
15.
Chrysin bonded to ß-d-glucose tetraacetate enhances its protective effects against the neurotoxicity induced by aluminum in Swiss mice.
J Pharm Pharmacol
; 76(4): 368-380, 2024 Apr 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-38330395
16.
A novel arylpiperazine derivative (LQFM181) protects against neurotoxicity induced by 3- nitropropionic acid in in vitro and in vivo models.
Chem Biol Interact
; 395: 111026, 2024 May 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-38679115
17.
Synthesis, docking studies, pharmacological activity and toxicity of a novel pyrazole derivative (LQFM 021)--possible effects on phosphodiesterase.
Chem Pharm Bull (Tokyo)
; 61(5): 524-31, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23649195
18.
Bioanalytical LC-QTOF/MS Method for a N-phenylpiperazine Derivate (LQFM05): An Anxiolytic- and Antidepressant-like Prototype Drug Applied to Pharmacokinetic and Biodistribution Studies.
Pharmaceuticals (Basel)
; 16(7)2023 Jun 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-37513842
19.
LQFM212, a piperazine derivative, exhibits potential antioxidant effect as well as ameliorates LPS-induced behavioral, inflammatory and oxidative changes.
Life Sci
; 312: 121199, 2023 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36402170
20.
L-proline transporter inhibitor (LQFM215) promotes neuroprotection in ischemic stroke.
Pharmacol Rep
; 75(2): 276-292, 2023 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-36719635