Detalles de la búsqueda
1.
Design, synthesis, and anticancer evaluation of N-sulfonylpiperidines as potential VEGFR-2 inhibitors, apoptotic inducers.
Bioorg Chem
; 145: 107157, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38340473
2.
Chemistry and Pharmacology of Delta-8-Tetrahydrocannabinol.
Molecules
; 29(6)2024 Mar 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-38542886
3.
LC/HRESI-MS/MS screening, phytochemical characterization, and in vitro antioxidant and cytotoxic potential of Jatropha integerrima Jacq. extracts.
Bioorg Chem
; 140: 106825, 2023 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37683543
4.
New apoptotic anti-triple-negative breast cancer theobromine derivative inhibiting EGFRWT and EGFRT790M: in silico and in vitro evaluation.
Mol Divers
; 2023 May 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-37162644
5.
Design, synthesis, docking, MD simulations, and anti-proliferative evaluation of thieno[2,3-d]pyrimidine derivatives as new EGFR inhibitors.
J Enzyme Inhib Med Chem
; 38(1): 2220579, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37288786
6.
A novel thieno[2,3-d]pyrimidine derivative inhibiting vascular endothelial growth factor receptor-2: A story of computer-aided drug discovery.
Drug Dev Res
; 84(6): 1247-1265, 2023 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37232504
7.
Computer-assisted drug discovery (CADD) of an anti-cancer derivative of the theobromine alkaloid inhibiting VEGFR-2.
Saudi Pharm J
; 31(12): 101852, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-38028225
8.
Discovery of new nicotinamides as apoptotic VEGFR-2 inhibitors: virtual screening, synthesis, anti-proliferative, immunomodulatory, ADMET, toxicity, and molecular dynamic simulation studies.
J Enzyme Inhib Med Chem
; 37(1): 1389-1403, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35577416
9.
Design and synthesis of thiazolidine-2,4-diones hybrids with 1,2-dihydroquinolones and 2-oxindoles as potential VEGFR-2 inhibitors: in-vitro anticancer evaluation and in-silico studies.
J Enzyme Inhib Med Chem
; 37(1): 1903-1917, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35801403
10.
Anti-cancer and immunomodulatory evaluation of new nicotinamide derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: in vitro and in silico studies.
J Enzyme Inhib Med Chem
; 37(1): 2206-2222, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35980113
11.
Design, synthesis, and anti-cancer evaluation of new pyrido[2,3-d]pyrimidin-4(3H)-one derivatives as potential EGFRWT and EGFRT790M inhibitors and apoptosis inducers.
J Enzyme Inhib Med Chem
; 37(1): 1053-1076, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35821615
12.
New quinoline and isatin derivatives as apoptotic VEGFR-2 inhibitors: design, synthesis, anti-proliferative activity, docking, ADMET, toxicity, and MD simulation studies.
J Enzyme Inhib Med Chem
; 37(1): 2191-2205, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35975321
13.
A Multistage In Silico Study of Natural Potential Inhibitors Targeting SARS-CoV-2 Main Protease.
Int J Mol Sci
; 23(15)2022 Jul 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-35955547
14.
Multi-Step In Silico Discovery of Natural Drugs against COVID-19 Targeting Main Protease.
Int J Mol Sci
; 23(13)2022 Jun 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-35805916
15.
New Anticancer Theobromine Derivative Targeting EGFRWT and EGFRT790M: Design, Semi-Synthesis, In Silico, and In Vitro Anticancer Studies.
Molecules
; 27(18)2022 Sep 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-36144596
16.
Design, Synthesis, Docking, DFT, MD Simulation Studies of a New Nicotinamide-Based Derivative: In Vitro Anticancer and VEGFR-2 Inhibitory Effects.
Molecules
; 27(14)2022 Jul 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-35889478
17.
Design, Synthesis, In Silico and In Vitro Studies of New Immunomodulatory Anticancer Nicotinamide Derivatives Targeting VEGFR-2.
Molecules
; 27(13)2022 Jun 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-35807326
18.
Expression, Purification, and Comparative Inhibition of Helicobacter pylori Urease by Regio-Selectively Alkylated Benzimidazole 2-Thione Derivatives.
Molecules
; 27(3)2022 Jan 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-35164122
19.
Isolation and In Silico Anti-SARS-CoV-2 Papain-Like Protease Potentialities of Two Rare 2-Phenoxychromone Derivatives from Artemisia spp.
Molecules
; 27(4)2022 Feb 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-35209006
20.
Jusanin, a New Flavonoid from Artemisia commutata with an In Silico Inhibitory Potential against the SARS-CoV-2 Main Protease.
Molecules
; 27(5)2022 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35268738