Detalles de la búsqueda
1.
Probing naphthalene diimide and 3-hydroxypropylphosphate as end-conjugating moieties for improved thrombin binding aptamers: Structural and biological effects.
Bioorg Chem
; 141: 106917, 2023 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37865055
2.
Modified Galacto- or Fuco-Clusters Exploiting the Siderophore Pathway to Inhibit the LecA- or LecB-Associated Virulence of Pseudomonas aeruginosa.
Chembiochem
; 21(23): 3433-3448, 2020 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32701213
3.
Fine-tuning the properties of the thrombin binding aptamer through cyclization: Effect of the 5'-3' connecting linker on the aptamer stability and anticoagulant activity.
Bioorg Chem
; 94: 103379, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31699393
4.
Design, Synthesis and Characterization of Cyclic NU172 Analogues: A Biophysical and Biological Insight.
Int J Mol Sci
; 21(11)2020 May 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-32485818
5.
Stability Is Not Everything: The Case of the Cyclisation of a Thrombin-Binding Aptamer.
Chembiochem
; 20(14): 1789-1794, 2019 07 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30860635
6.
Solid Supports for the Synthesis of 3'-Aminooxy Deoxy- or Ribo-oligonucleotides and Their 3'-Conjugation by Oxime Ligation.
J Org Chem
; 84(22): 14854-14860, 2019 11 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31615211
7.
Screening of a Library of Oligosaccharides Targeting Lectin LecB of Pseudomonas Aeruginosa and Synthesis of High Affinity Oligoglycoclusters.
Molecules
; 23(12)2018 Nov 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-30477231
8.
Design and Synthesis of Galactosylated Bifurcated Ligands with Nanomolar Affinity for Lectin LecA from Pseudomonas aeruginosa.
Chembiochem
; 18(11): 1036-1047, 2017 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28318079
9.
Improved Performance of DNA Microarray Multiplex Hybridization Using Probes Anchored at Several Points by Thiol-Ene or Thiol-Yne Coupling Chemistry.
Bioconjug Chem
; 28(2): 496-506, 2017 02 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28042940
10.
Toward the Rational Design of Galactosylated Glycoclusters That Target Pseudomonas aeruginosa Lectin A (LecA): Influence of Linker Arms That Lead to Low-Nanomolar Multivalent Ligands.
Chemistry
; 22(33): 11785-94, 2016 Aug 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27412649
11.
Effects of the Surface Densities of Glycoclusters on the Determination of Their IC50 and Kd Value Determination by Using a Microarray.
Chembiochem
; 16(16): 2329-36, 2015 Nov 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-26360327
12.
Importance of topology for glycocluster binding to Pseudomonas aeruginosa and Burkholderia ambifaria bacterial lectins.
Org Biomol Chem
; 13(46): 11244-54, 2015 Dec 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-26412676
13.
Mannose-centered aromatic galactoclusters inhibit the biofilm formation of Pseudomonas aeruginosa.
Org Biomol Chem
; 13(31): 8433-44, 2015 Aug 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-26090586
14.
Structure binding relationship of galactosylated Glycoclusters toward Pseudomonas aeruginosa lectin LecA using a DNA-based carbohydrate microarray.
Bioconjug Chem
; 25(2): 379-92, 2014 Feb 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-24479549
15.
The influence of the aromatic aglycon of galactoclusters on the binding of LecA: a case study with O-phenyl, S-phenyl, O-benzyl, S-benzyl, O-biphenyl and O-naphthyl aglycons.
Org Biomol Chem
; 12(45): 9166-79, 2014 Dec 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-25295668
16.
Development of innovative and versatile polythiol probes for use on ELOSA or electrochemical biosensors: application in hepatitis C virus genotyping.
Anal Chem
; 85(19): 9204-12, 2013 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24050654
17.
Fluorescence enhancement upon G-quadruplex folding: synthesis, structure, and biophysical characterization of a dansyl/cyclodextrin-tagged thrombin binding aptamer.
Bioconjug Chem
; 24(11): 1917-27, 2013 Nov 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-24094251
18.
Synthesis of a library of fucosylated glycoclusters and determination of their binding toward Pseudomonas aeruginosa lectin B (PA-IIL) using a DNA-based carbohydrate microarray.
Bioconjug Chem
; 23(8): 1534-47, 2012 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22799498
19.
Synthesis of homo- and heterofunctionalized glycoclusters and binding to Pseudomonas aeruginosa lectins PA-IL and PA-IIL.
J Org Chem
; 77(17): 7620-6, 2012 Sep 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-22873634
20.
Measurement of enzymatic activity and specificity of human and avian influenza neuraminidases from whole virus by glycoarray and MALDI-TOF mass spectrometry.
Chembiochem
; 12(13): 2071-80, 2011 Sep 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-21739555