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1.
TRP14 is the rate-limiting enzyme for intracellular cystine reduction and regulates proteome cysteinylation.
EMBO J
; 2024 May 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-38811853
2.
The Melatonin Derivative ITH13001 Prevents Hypertension and Cardiovascular Alterations in Angiotensin II-Infused Mice.
J Pharmacol Exp Ther
; 388(2): 670-687, 2024 01 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-38129126
3.
A chemical screen for modulators of mRNA translation identifies a distinct mechanism of toxicity for sphingosine kinase inhibitors.
PLoS Biol
; 19(5): e3001263, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34033645
4.
New Nrf2-Inducer Compound ITH12674 Slows the Progression of Retinitis Pigmentosa in the Mouse Model rd10.
Cell Physiol Biochem
; 54(1): 142-159, 2020 Feb 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32028545
5.
Melatonin-sulforaphane hybrid ITH12674 attenuates glial response in vivo by blocking LPS binding to MD2 and receptor oligomerization.
Pharmacol Res
; 152: 104597, 2020 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31838078
6.
Aza-CGP37157-lipoic hybrids designed as novel Nrf2-inducers and antioxidants exert neuroprotection against oxidative stress and show neuroinflammation inhibitory properties.
Drug Dev Res
; 81(3): 283-294, 2020 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-31693218
7.
Pharmacological doses of melatonin impede cognitive decline in tau-related Alzheimer models, once tauopathy is initiated, by restoring the autophagic flux.
J Pineal Res
; 67(1): e12578, 2019 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-30943316
8.
Novel Series of Dual NRF2 Inducers and Selective MAO-B Inhibitors for the Treatment of Parkinson's Disease.
Antioxidants (Basel)
; 11(2)2022 Jan 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-35204129
9.
Enantioselective Synthesis and Pharmacological Evaluation of Aza-CGP37157-Lipoic Acid Hybrids for the Treatment of Alzheimer's Disease.
Antioxidants (Basel)
; 11(1)2022 Jan 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-35052616
10.
Resveratrol-Based MTDLs to Stimulate Defensive and Regenerative Pathways and Block Early Events in Neurodegenerative Cascades.
J Med Chem
; 65(6): 4727-4751, 2022 03 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-35245051
11.
Fear of Cancer Progression and Health Behaviors in Patients with Colorectal Cancer.
Am J Health Behav
; 45(1): 138-151, 2021 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33402244
12.
Bisavenathramide Analogues as Nrf2 Inductors and Neuroprotectors in In Vitro Models of Oxidative Stress and Hyperphosphorylation.
Antioxidants (Basel)
; 10(6)2021 Jun 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34200859
13.
Enhanced Stability and Bioactivity of Natural Anticancer Topoisomerase I Inhibitors through Cyclodextrin Complexation.
Pharmaceutics
; 13(10)2021 Oct 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-34683902
14.
When It Comes to an End: Oxidative Stress Crosstalk with Protein Aggregation and Neuroinflammation Induce Neurodegeneration.
Antioxidants (Basel)
; 9(8)2020 Aug 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-32806679
15.
Perspective of Internet Poker Players on Harm-Reduction Strategies: A Cross-Sectional Study.
Int J Environ Res Public Health
; 17(23)2020 12 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33291669
16.
Antioxidant, Anti-inflammatory and Neuroprotective Profiles of Novel 1,4-Dihydropyridine Derivatives for the Treatment of Alzheimer's Disease.
Antioxidants (Basel)
; 9(8)2020 Jul 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-32708053
17.
Tuning melatonin receptor subtype selectivity in oxadiazolone-based analogues: Discovery of QR2 ligands and NRF2 activators with neurogenic properties.
Eur J Med Chem
; 190: 112090, 2020 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32018096
18.
The angiotensin-(1-7)/Mas receptor axis protects from endothelial cell senescence via klotho and Nrf2 activation.
Aging Cell
; 18(3): e12913, 2019 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-30773786
19.
Nrf2 Plays a Protective Role Against Intravascular Hemolysis-Mediated Acute Kidney Injury.
Front Pharmacol
; 10: 740, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31333462
20.
MAFG is a potential therapeutic target to restore chemosensitivity in cisplatin-resistant cancer cells by increasing reactive oxygen species.
Transl Res
; 200: 1-17, 2018 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-30053382