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1.
Host Poly(A) Polymerases PAPD5 and PAPD7 Provide Two Layers of Protection That Ensure the Integrity and Stability of Hepatitis B Virus RNA.
J Virol
; 95(18): e0057421, 2021 08 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-34191584
2.
Preclinical Profile of AB-423, an Inhibitor of Hepatitis B Virus Pregenomic RNA Encapsidation.
Antimicrob Agents Chemother
; 62(6)2018 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29555628
3.
Discovery of C-Linked Nucleoside Analogues with Antiviral Activity against SARS-CoV-2.
ACS Infect Dis
; 10(5): 1780-1792, 2024 05 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-38651692
4.
Genotype and subtype profiling of PSI-7977 as a nucleotide inhibitor of hepatitis C virus.
Antimicrob Agents Chemother
; 56(6): 3359-68, 2012 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-22430955
5.
Hepatitis C virus nucleotide inhibitors PSI-352938 and PSI-353661 exhibit a novel mechanism of resistance requiring multiple mutations within replicon RNA.
J Virol
; 85(23): 12334-42, 2011 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-21957306
6.
ß-D-2'-α-F-2'-ß-C-Methyl-6-O-substituted 3',5'-cyclic phosphate nucleotide prodrugs as inhibitors of hepatitis C virus replication: a structure-activity relationship study.
Bioorg Med Chem Lett
; 22(18): 5924-9, 2012 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22892115
7.
Preclinical characterization of AB-506, an inhibitor of HBV replication targeting the viral core protein.
Antiviral Res
; 197: 105211, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34826506
8.
Inhibition of hepatitis C virus replicon RNA synthesis by PSI-352938, a cyclic phosphate prodrug of ß-D-2'-deoxy-2'-α-fluoro-2'-ß-C-methylguanosine.
Antimicrob Agents Chemother
; 55(6): 2566-75, 2011 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-21444700
9.
Use of 2'-spirocyclic ethers in HCV nucleoside design.
J Med Chem
; 57(5): 1826-35, 2014 Mar 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-24079820
10.
Evaluation of the in vitro anti-HBV activity of clevudine in combination with other nucleoside/nucleotide inhibitors.
Antivir Ther
; 15(3): 401-12, 2010.
Artículo
en Inglés
| MEDLINE | ID: mdl-20516559
11.
The mechanism of action of beta-D-2'-deoxy-2'-fluoro-2'-C-methylcytidine involves a second metabolic pathway leading to beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine 5'-triphosphate, a potent inhibitor of the hepatitis C virus RNA-dependent RNA polymerase.
Antimicrob Agents Chemother
; 52(2): 458-64, 2008 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-17999967
12.
Mechanism of activation of beta-D-2'-deoxy-2'-fluoro-2'-c-methylcytidine and inhibition of hepatitis C virus NS5B RNA polymerase.
Antimicrob Agents Chemother
; 51(2): 503-9, 2007 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-17101674
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