Detalles de la búsqueda
1.
Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens.
Nature
; 568(7753): 511-516, 2019 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30971826
2.
The genomic landscape of response to EGFR blockade in colorectal cancer.
Nature
; 526(7572): 263-7, 2015 Oct 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-26416732
3.
HSP27 is required for invasion and metastasis triggered by hepatocyte growth factor.
Int J Cancer
; 134(6): 1289-99, 2014 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23996744
4.
Purinergic signaling inhibits human acute myeloblastic leukemia cell proliferation, migration, and engraftment in immunodeficient mice.
Blood
; 119(1): 217-26, 2012 Jan 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-22053107
5.
Case report: Preclinical efficacy of NEDD8 and proteasome inhibitors in patient-derived models of signet ring high-grade mucinous colorectal cancer from a Lynch syndrome patient.
Front Oncol
; 13: 1130852, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36816936
6.
Phosphoproteomics of patient-derived xenografts identifies targets and markers associated with sensitivity and resistance to EGFR blockade in colorectal cancer.
Sci Transl Med
; 15(709): eabm3687, 2023 08 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-37585503
7.
Inhibition of erythropoiesis in malaria anemia: role of hemozoin and hemozoin-generated 4-hydroxynonenal.
Blood
; 116(20): 4328-37, 2010 Nov 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-20686121
8.
HER2-positive breast cancer cells resistant to trastuzumab and lapatinib lose reliance upon HER2 and are sensitive to the multitargeted kinase inhibitor sorafenib.
Breast Cancer Res Treat
; 130(1): 29-40, 2011 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-21153051
9.
Epidermal Growth Factor Receptor (EGFR) mutation analysis, gene expression profiling and EGFR protein expression in primary prostate cancer.
BMC Cancer
; 11: 31, 2011 Jan 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-21266046
10.
Molecular Subtyping Combined with Biological Pathway Analyses to Study Regorafenib Response in Clinically Relevant Mouse Models of Colorectal Cancer.
Clin Cancer Res
; 27(21): 5979-5992, 2021 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34426441
11.
Efficient transcriptional targeting of human hematopoietic stem cells and blood cell lineages by lentiviral vectors containing the regulatory element of the Wiskott-Aldrich syndrome gene.
Stem Cells
; 27(11): 2815-23, 2009 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-19785032
12.
Targeting EGFR/HER2 pathways enhances the antiproliferative effect of gemcitabine in biliary tract and gallbladder carcinomas.
BMC Cancer
; 10: 631, 2010 Nov 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-21087480
13.
Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell-like phenotype.
Sci Transl Med
; 12(555)2020 08 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-32759276
14.
Sorafenib blocks tumour growth, angiogenesis and metastatic potential in preclinical models of osteosarcoma through a mechanism potentially involving the inhibition of ERK1/2, MCL-1 and ezrin pathways.
Mol Cancer
; 8: 118, 2009 Dec 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-20003259
15.
Combined blockade of MEK and PI3KCA as an effective antitumor strategy in HER2 gene amplified human colorectal cancer models.
J Exp Clin Cancer Res
; 38(1): 236, 2019 Jun 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-31164152
16.
Efficacy of NEDD8 Pathway Inhibition in Preclinical Models of Poorly Differentiated, Clinically Aggressive Colorectal Cancer.
J Natl Cancer Inst
; 109(2)2017 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-27771609
17.
C-met inhibition blocks bone metastasis development induced by renal cancer stem cells.
Oncotarget
; 7(29): 45525-45537, 2016 Jul 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-27322553
18.
Sustained Inhibition of HER3 and EGFR Is Necessary to Induce Regression of HER2-Amplified Gastrointestinal Carcinomas.
Clin Cancer Res
; 21(24): 5519-31, 2015 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26296355
19.
HER2 activating mutations are targets for colorectal cancer treatment.
Cancer Discov
; 5(8): 832-41, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-26243863
20.
The tissue inhibitor of metalloproteinases 1 increases the clonogenic efficiency of human hematopoietic progenitor cells through CD63/PI3K/Akt signaling.
Exp Hematol
; 43(11): 974-985.e1, 2015 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-26213230