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1.
Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1.
Cell
; 161(7): 1633-43, 2015 Jun 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-26091040
2.
Structure of the human κ-opioid receptor in complex with JDTic.
Nature
; 485(7398): 327-32, 2012 Mar 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-22437504
3.
Fluoride-mediated capture of a noncovalent bound state of a reversible covalent enzyme inhibitor: X-ray crystallographic analysis of an exceptionally potent α-ketoheterocycle inhibitor of fatty acid amide hydrolase.
J Am Chem Soc
; 133(11): 4092-100, 2011 Mar 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-21355555
4.
Structure-guided inhibitor design for human FAAH by interspecies active site conversion.
Proc Natl Acad Sci U S A
; 105(35): 12820-4, 2008 Sep 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-18753625
5.
Microscale fluorescent thermal stability assay for membrane proteins.
Structure
; 16(3): 351-9, 2008 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-18334210
6.
Binding and inactivation mechanism of a humanized fatty acid amide hydrolase by alpha-ketoheterocycle inhibitors revealed from cocrystal structures.
J Am Chem Soc
; 131(30): 10497-506, 2009 Aug 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-19722626
7.
Correlation of inhibitor effects on enzyme activity and thermal stability for the integral membrane protein fatty acid amide hydrolase.
Bioorg Med Chem Lett
; 18(22): 5847-50, 2008 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18644727
8.
Recent progress on obtaining theoretical and experimental support for the "E-pathway hypothesis" of coupled transmembrane electron and proton transfer in dihaem-containing quinol:fumarate reductase.
Biochim Biophys Acta
; 1757(8): 988-95, 2006 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-16790236
9.
Heterologous production in Wolinella succinogenes and characterization of the quinol:fumarate reductase enzymes from Helicobacter pylori and Campylobacter jejuni.
Biochem J
; 395(1): 191-201, 2006 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16367742
10.
The N-terminal sequence of tyrosine hydroxylase is a conformationally versatile motif that binds 14-3-3 proteins and membranes.
J Mol Biol
; 426(1): 150-68, 2014 Jan 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-24055376
11.
The crystal structure of the α-neurexin-1 extracellular region reveals a hinge point for mediating synaptic adhesion and function.
Structure
; 19(6): 767-78, 2011 Jun 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-21620717
12.
Label-free quantification of membrane-ligand interactions using backscattering interferometry.
Nat Biotechnol
; 29(4): 357-60, 2011 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-21399645
13.
Understanding the role of carbamate reactivity in fatty acid amide hydrolase inhibition by QM/MM mechanistic modelling.
Chem Commun (Camb)
; 47(9): 2517-9, 2011 Mar 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-21240393
14.
Reversible competitive α-ketoheterocycle inhibitors of fatty acid amide hydrolase containing additional conformational constraints in the acyl side chain: orally active, long-acting analgesics.
J Med Chem
; 54(8): 2805-22, 2011 Apr 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-21428410
15.
X-ray crystallographic analysis of alpha-ketoheterocycle inhibitors bound to a humanized variant of fatty acid amide hydrolase.
J Med Chem
; 53(1): 230-40, 2010 Jan 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-19924997
16.
Crystal structure of fatty acid amide hydrolase bound to the carbamate inhibitor URB597: discovery of a deacylating water molecule and insight into enzyme inactivation.
J Mol Biol
; 400(4): 743-54, 2010 Jul 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-20493882
17.
Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain.
Chem Biol
; 16(4): 411-20, 2009 Apr 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-19389627
18.
Probing heme propionate involvement in transmembrane proton transfer coupled to electron transfer in dihemic quinol:fumarate reductase by 13C-labeling and FTIR difference spectroscopy.
Biochemistry
; 44(50): 16718-28, 2005 Dec 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-16342962
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