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1.
Model-informed drug development of autologous CAR-T cell therapy: Strategies to optimize CAR-T cell exposure leveraging cell kinetic/dynamic modeling.
CPT Pharmacometrics Syst Pharmacol
; 12(11): 1577-1590, 2023 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-37448343
2.
Pharmacokinetics, safety, and tolerability of voriconazole in immunocompromised children.
Antimicrob Agents Chemother
; 54(10): 4116-23, 2010 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-20660687
3.
Population pharmacokinetic analysis of voriconazole plasma concentration data from pediatric studies.
Antimicrob Agents Chemother
; 53(3): 935-44, 2009 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-19075073
4.
Assessing the efficiency of mixed effects modelling in quantifying metabolism based drug-drug interactions: using in vitro data as an aid to assess study power.
Pharm Stat
; 8(3): 186-202, 2009.
Artículo
en Inglés
| MEDLINE | ID: mdl-19291743
5.
A non-parametric method to analyse time-course of effect in the absence of pharmacokinetic data: application to inhaled bronchodilators.
Eur J Pharm Sci
; 34(4-5): 250-6, 2008 Aug 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-18547791
6.
Model Informed Drug Development: Collaboration Through A Common Framework.
Clin Pharmacol Ther
; 110(5): 1165-1167, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-33111309
7.
Model-based prediction of progression-free survival in patients with first-line renal cell carcinoma using week 8 tumor size change from baseline.
Cancer Chemother Pharmacol
; 78(3): 605-10, 2016 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-27468922
8.
A pharmacokinetic-pharmacodynamic model for the quantitative prediction of dofetilide clinical QT prolongation from human ether-a-go-go-related gene current inhibition data.
Clin Pharmacol Ther
; 77(6): 572-82, 2005 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-15961988
9.
Modeling and simulations relating overall survival to tumor growth inhibition in renal cell carcinoma patients.
Cancer Chemother Pharmacol
; 76(3): 567-73, 2015 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-26198314
10.
A population pharmacokinetic analysis of sildenafil citrate in patients with erectile dysfunction.
Br J Clin Pharmacol
; 53 Suppl 1: 45S-52S, 2002.
Artículo
en Inglés
| MEDLINE | ID: mdl-11879259
11.
Assessment of the relative in vivo potency of the hydroxylated metabolite of darifenacin in its ability to decrease salivary flow using pooled population pharmacokinetic-pharmacodynamic data.
Br J Clin Pharmacol
; 57(2): 170-80, 2004 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-14748816
12.
Models for time-varying covariates in population pharmacokinetic-pharmacodynamic analysis.
Br J Clin Pharmacol
; 58(4): 367-77, 2004 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-15373929
13.
Population pharmacokinetic modelling of darifenacin and its hydroxylated metabolite using pooled data, incorporating saturable first-pass metabolism, CYP2D6 genotype and formulation-dependent bioavailability.
Br J Clin Pharmacol
; 56(6): 639-52, 2003 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-14616424
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