Detalles de la búsqueda
1.
A benzopyran with antiarrhythmic activity is an inhibitor of Kir3.1-containing potassium channels.
J Biol Chem
; 296: 100535, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-33713702
2.
Novel K+ Channel Targets in Atrial Fibrillation Drug Development--Where Are We?
J Cardiovasc Pharmacol
; 66(5): 412-31, 2015 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-25978691
3.
Human electrophysiological and pharmacological properties of XEN-D0101: a novel atrial-selective Kv1.5/IKur inhibitor.
J Cardiovasc Pharmacol
; 61(5): 408-15, 2013 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-23364608
4.
Pharmacological inhibition of acetylcholine-regulated potassium current (I K,ACh) prevents atrial arrhythmogenic changes in a rat model of repetitive obstructive respiratory events.
Heart Rhythm O2
; 3(1): 97-104, 2022 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-35243441
5.
Characterisation of AnBEST1, a functional anion channel in the plasma membrane of the filamentous fungus, Aspergillus nidulans.
Fungal Genet Biol
; 48(9): 928-38, 2011 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-21596151
6.
The Acetylcholine-Activated Potassium Current Inhibitor XAF-1407 Terminates Persistent Atrial Fibrillation in Goats.
Front Pharmacol
; 11: 608410, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-33584287
7.
Inhibition of voltage-gated Na+ currents by eleclazine in rat atrial and ventricular myocytes.
Heart Rhythm O2
; 1(3): 206-214, 2020 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-32864638
8.
Lightsheet fluorescence lifetime imaging microscopy with wide-field time-correlated single photon counting.
J Biophotonics
; 13(2): e201960099, 2020 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31661595
9.
Effect of selective IK,ACh inhibition by XAF-1407 in an equine model of tachypacing-induced persistent atrial fibrillation.
Br J Pharmacol
; 177(16): 3778-3794, 2020 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32436234
10.
Wide-field time-correlated single photon counting-based fluorescence lifetime imaging microscopy.
Nucl Instrum Methods Phys Res A
; 942: 162365, 2019 Oct 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-31645797
11.
Genetic variation in GNB5 causes bradycardia by augmenting the cholinergic response via increased acetylcholine-activated potassium current (IK,ACh).
Dis Model Mech
; 12(7)2019 07 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-31208990
12.
New drugs targeting the cardiac ultra-rapid delayed-rectifier current (I Kur): rationale, pharmacology and evidence for potential therapeutic value.
J Cardiovasc Pharmacol
; 52(2): 105-20, 2008 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-18670369
13.
Inhibition of the HERG K+ channel by the antifungal drug ketoconazole depends on channel gating and involves the S6 residue F656.
FEBS Lett
; 580(8): 1999-2005, 2006 Apr 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-16542653
14.
A wide-field TCSPC FLIM system based on an MCP PMT with a delay-line anode.
Rev Sci Instrum
; 87(9): 093710, 2016 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-27782585
15.
The positive frequency-dependent electrophysiological effects of the IKur inhibitor XEN-D0103 are desirable for the treatment of atrial fibrillation.
Heart Rhythm
; 13(2): 555-64, 2016 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-26455450
16.
Atrial-like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial-selective pharmacology.
EMBO Mol Med
; 7(4): 394-410, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25700171
17.
Preferential closed channel blockade of HERG potassium currents by chemically synthesised BeKm-1 scorpion toxin.
FEBS Lett
; 547(1-3): 20-6, 2003 Jul 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-12860380
18.
Blockade of HERG potassium currents by fluvoxamine: incomplete attenuation by S6 mutations at F656 or Y652.
Br J Pharmacol
; 139(5): 887-98, 2003 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-12839862
19.
Troubleshooting problems with in vitro screening of drugs for QT interval prolongation using HERG K+ channels expressed in mammalian cell lines and Xenopus oocytes.
J Pharmacol Toxicol Methods
; 48(2): 65-80, 2002.
Artículo
en Inglés
| MEDLINE | ID: mdl-14565563
20.
Effects of IKur blocker MK-0448 on human right atrial action potentials from patients in sinus rhythm and in permanent atrial fibrillation.
Front Pharmacol
; 5: 26, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24624083