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1.
Drug hypersensitivity reactions: review of the state of the science for prediction and diagnosis.
Toxicol Sci
; 2024 Apr 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-38588579
2.
Current approaches to evaluate the function of cytotoxic T-cells in non-human primates.
J Immunotoxicol
; 20(1): 2176952, 2023 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-36788724
3.
The COMPARE Database: A Public Resource for Allergen Identification, Adapted for Continuous Improvement.
Front Allergy
; 2: 700533, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-35386979
4.
Novel 5-substituted pyrrolo[2,3-d]pyrimidines as dual inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase and as potential antitumor agents.
J Med Chem
; 58(3): 1479-93, 2015 Feb 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-25602637
5.
6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Regioisomers as Targeted Antifolates for Folate Receptor α and the Proton-Coupled Folate Transporter in Human Tumors.
J Med Chem
; 58(17): 6938-59, 2015 Sep 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-26317331
6.
Tumor-targeting with novel non-benzoyl 6-substituted straight chain pyrrolo[2,3-d]pyrimidine antifolates via cellular uptake by folate receptor α and inhibition of de novo purine nucleotide biosynthesis.
J Med Chem
; 56(21): 8684-95, 2013 Nov 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-24111942
7.
Discovery of 5-substituted pyrrolo[2,3-d]pyrimidine antifolates as dual-acting inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase in de novo purine nucleotide biosynthesis: implications of inhibiting 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase to ampk activation and antitumor activity.
J Med Chem
; 56(24): 10016-10032, 2013 Dec 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-24256410
8.
Synthesis and biological activity of 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl regioisomers as inhibitors of de novo purine biosynthesis with selectivity for cellular uptake by high affinity folate receptors and the proton-coupled folate transporter over the reduced folate carrier.
J Med Chem
; 55(4): 1758-70, 2012 Feb 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-22243528
9.
Synthesis, biological, and antitumor activity of a highly potent 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate inhibitor with proton-coupled folate transporter and folate receptor selectivity over the reduced folate carrier that inhibits ß-glycinamide ribonucleotide formyltransferase.
J Med Chem
; 54(20): 7150-64, 2011 Oct 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-21879757
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