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1.
Triazole- and Tetrazole-Bridged Nucleic Acids: Synthesis, Duplex Stability, Nuclease Resistance, and in Vitro and in Vivo Antisense Potency.
J Org Chem
; 82(1): 12-24, 2017 01 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-27936689
2.
Effect of an N-substituent in sulfonamide-bridged nucleic acid (SuNA) on hybridization ability and duplex structure.
Org Biomol Chem
; 14(27): 6531-8, 2016 Jul 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-27296230
3.
A unique hinge binder of extremely selective aminopyridine-based Mps1 (TTK) kinase inhibitors with cellular activity.
Bioorg Med Chem
; 23(9): 2247-60, 2015 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25801152
4.
A bridged nucleic acid, 2',4'-BNA COC: synthesis of fully modified oligonucleotides bearing thymine, 5-methylcytosine, adenine and guanine 2',4'-BNA COC monomers and RNA-selective nucleic-acid recognition.
Nucleic Acids Res
; 37(4): 1225-38, 2009 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-19136459
5.
Balancing potency and basicity by incorporating fluoropyridine moieties: Discovery of a 1-amino-3,4-dihydro-2,6-naphthyridine BACE1 inhibitor that affords robust and sustained central Aß reduction.
Eur J Med Chem
; 216: 113270, 2021 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33765486
6.
RNA Reduction and Hepatotoxic Potential Caused by Non-Gapmer Antisense Oligonucleotides.
Nucleic Acid Ther
; 29(1): 44-50, 2019 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30508397
7.
Rational Design of Novel 1,3-Oxazine Based ß-Secretase (BACE1) Inhibitors: Incorporation of a Double Bond To Reduce P-gp Efflux Leading to Robust Aß Reduction in the Brain.
J Med Chem
; 61(12): 5122-5137, 2018 06 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-29733614
8.
Synthesis of novel 2'-deoxy type trans-3',4'-bridged nucleic acid.
Nucleosides Nucleotides Nucleic Acids
; 26(8-9): 1079-82, 2007.
Artículo
en Inglés
| MEDLINE | ID: mdl-18058540
9.
Sulfonamide-bridged nucleic acid: synthesis, high RNA selective hybridization, and high nuclease resistance.
Org Lett
; 16(21): 5640-3, 2014 Nov 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-25341881
10.
Synthesis and properties of a 2'-deoxy analogue of trans-3',4'-BNA with an S-type sugar conformation.
Nucleic Acids Symp Ser (Oxf)
; (51): 155-6, 2007.
Artículo
en Inglés
| MEDLINE | ID: mdl-18029633
11.
Synthesis of 2',4'-BNACOC bearing a purine nucleobase.
Nucleic Acids Symp Ser (Oxf)
; (50): 13-4, 2006.
Artículo
en Inglés
| MEDLINE | ID: mdl-17150793
12.
Synthesis and properties of trans-3',4'-bridged nucleic acids having typical S-type sugar conformation.
J Org Chem
; 71(4): 1306-16, 2006 Feb 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-16468776
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