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1.
Optimized methods for targeted peptide-based quantification of human uridine 5'-diphosphate-glucuronosyltransferases in biological specimens using liquid chromatography-tandem mass spectrometry.
Drug Metab Dispos
; 42(5): 885-9, 2014 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-24595681
2.
Intestinal absorption mechanism of mirabegron, a potent and selective ß3-adrenoceptor agonist: involvement of human efflux and/or influx transport systems.
Mol Pharm
; 10(5): 1783-94, 2013 May 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-23560393
3.
Absorption, metabolism and excretion of darexaban (YM150), a new direct factor Xa inhibitor in humans.
Xenobiotica
; 43(6): 534-47, 2013 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-23167531
4.
Conclusive identification of the oxybutynin-hydrolyzing enzyme in human liver.
Drug Metab Dispos
; 40(5): 902-6, 2012 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-22293119
5.
Simultaneous absolute protein quantification of carboxylesterases 1 and 2 in human liver tissue fractions using liquid chromatography-tandem mass spectrometry.
Drug Metab Dispos
; 40(7): 1389-96, 2012 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-22504157
6.
Identification of UDP-glucuronosyltransferases responsible for the glucuronidation of darexaban, an oral factor Xa inhibitor, in human liver and intestine.
Drug Metab Dispos
; 40(2): 276-82, 2012 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-22031623
7.
Absorption, metabolism and excretion of [(14)C]mirabegron (YM178), a potent and selective ß(3)-adrenoceptor agonist, after oral administration to healthy male volunteers.
Drug Metab Dispos
; 40(4): 815-24, 2012 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-22269146
8.
Identification of enzymes responsible for the N-oxidation of darexaban glucuronide, the pharmacologically active metabolite of darexaban, and the glucuronidation of darexaban N-oxides in human liver microsomes.
Biol Pharm Bull
; 35(3): 413-21, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22382330
9.
In vitro inhibition and induction of human cytochrome P450 enzymes by mirabegron, a potent and selective ß3-adrenoceptor agonist.
Xenobiotica
; 42(12): 1187-96, 2012 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-22834478
10.
Protein quantification of UDP-glucuronosyltransferases 1A1 and 2B7 in human liver microsomes by LC-MS/MS and correlation with glucuronidation activities.
Xenobiotica
; 42(9): 823-9, 2012 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-22435749
11.
Identification of human cytochrome P450 isoforms and esterases involved in the metabolism of mirabegron, a potent and selective ß3-adrenoceptor agonist.
Xenobiotica
; 42(10): 957-67, 2012 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-22509825
12.
Pharmacokinetics, distribution and excretion of YM155 monobromide, a novel small-molecule survivin suppressant, in male and pregnant or lactating female rats.
Biopharm Drug Dispos
; 33(3): 160-9, 2012 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-22374735
13.
The Pharmacokinetics of Beraprost Sodium Following Single Oral Administration to Subjects With Impaired Kidney Function.
J Clin Pharmacol
; 57(4): 524-535, 2017 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-27681484
14.
Placental transfer of intravenous nicardipine and disposition into breast milk during the control of hypertension in women with pre-eclampsia.
Hypertens Pregnancy
; 33(1): 93-101, 2014 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-24131296
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