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1.
1,6-Disubstituted indole derivatives as selective human neuronal nitric oxide synthase inhibitors.
Bioorg Med Chem Lett
; 21(18): 5234-8, 2011 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21824773
2.
Photochemical generation of 9H-fluorenyl radicals.
Photochem Photobiol
; 90(2): 470-5, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24329554
3.
First-in-class, dual-action, 3,5-disubstituted indole derivatives having human nitric oxide synthase (nNOS) and norepinephrine reuptake inhibitory (NERI) activity for the treatment of neuropathic pain.
J Med Chem
; 55(7): 3488-501, 2012 Apr 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-22420844
4.
Discovery of cis-N-(1-(4-(methylamino)cyclohexyl)indolin-6-yl)thiophene-2-carboximidamide: a 1,6-disubstituted indoline derivative as a highly selective inhibitor of human neuronal nitric oxide synthase (nNOS) without any cardiovascular liabilities.
J Med Chem
; 55(2): 943-55, 2012 Jan 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-22175766
5.
Discovery of a potent, orally bioavailable and highly selective human neuronal nitric oxide synthase (nNOS) inhibitor, N-(1-(piperidin-4-yl)indolin-5-yl)thiophene-2-carboximidamide as a pre-clinical development candidate for the treatment of migraine.
Eur J Med Chem
; 55: 94-107, 2012 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-22840695
6.
1,2,3,4-tetrahydroquinoline-based selective human neuronal nitric oxide synthase (nNOS) inhibitors: lead optimization studies resulting in the identification of N-(1-(2-(methylamino)ethyl)-1,2,3,4-tetrahydroquinolin-6-yl)thiophene-2-carboximidamide as a preclinical development candidate.
J Med Chem
; 55(6): 2882-93, 2012 Mar 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-22335555
7.
Discovery of N-(3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indol-6-yl) thiophene-2-carboximidamide as a selective inhibitor of human neuronal nitric oxide synthase (nNOS) for the treatment of pain.
J Med Chem
; 54(20): 7408-16, 2011 Oct 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-21923116
8.
Design, synthesis, and biological evaluation of 3,4-dihydroquinolin-2(1H)-one and 1,2,3,4-tetrahydroquinoline-based selective human neuronal nitric oxide synthase (nNOS) inhibitors.
J Med Chem
; 54(15): 5562-75, 2011 Aug 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-21699209
9.
Photochemical pinacol rearrangements of unsymmetrical diols.
J Org Chem
; 69(6): 2017-23, 2004 Mar 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-15058948
10.
Enantiomerically pure cyclobutane derivatives and their use in organic synthesis.
Chem Rev
; 103(4): 1449-83, 2003 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-12683788
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