Detalles de la búsqueda
1.
Design, synthesis, molecular modelling and biological evaluation of novel 6-amino-5-cyano-2-thiopyrimidine derivatives as potent anticancer agents against leukemia and apoptotic inducers.
J Enzyme Inhib Med Chem
; 39(1): 2304625, 2024 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-38348824
2.
Novel benzo chromene derivatives: design, synthesis, molecular docking, cell cycle arrest, and apoptosis induction in human acute myeloid leukemia HL-60 cells.
J Enzyme Inhib Med Chem
; 38(1): 405-422, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-36458403
3.
Design, synthesis, and antitumor efficacy of novel 5-deazaflavin derivatives backed by kinase screening, docking, and ADME studies.
J Enzyme Inhib Med Chem
; 38(1): 2220570, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37341389
4.
Utility of novel 2-furanones in synthesis of other heterocyclic compounds having anti-inflammatory activity with dual COX2/LOX inhibition.
J Enzyme Inhib Med Chem
; 36(1): 977-986, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-33957835
5.
Design, Synthesis, Antitumor Activity and Molecular Docking Study of Novel 5-Deazaalloxazine Analogs.
Molecules
; 25(11)2020 May 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-32481639
6.
Molecular modelling insights into a physiologically favourable approach to eicosanoid biosynthesis inhibition through novel thieno[2,3-b]pyridine derivatives.
J Enzyme Inhib Med Chem
; 33(1): 755-767, 2018 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-29651867
7.
Indole-based allosteric inhibitors of HIV-1 integrase.
Bioorg Med Chem Lett
; 26(19): 4748-4752, 2016 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27568085
8.
Design, synthesis, assessment, and molecular docking of novel pyrrolopyrimidine (7-deazapurine) derivatives as non-nucleoside hepatitis C virus NS5B polymerase inhibitors.
Bioorg Med Chem
; 24(9): 2146-57, 2016 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27052365
9.
Novel antiviral compounds against gastroenteric viral infections.
Arch Pharm (Weinheim)
; 348(3): 194-205, 2015 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-25704120
10.
Synthesis of new pyrroles of potential anti-inflammatory activity.
Arch Pharm (Weinheim)
; 344(12): 830-9, 2011 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-21956581
11.
Synthesis, biological evaluation and molecular docking of quinazoline-4(1H)-one derivatives as anti-inflammatory and analgesic agents.
Acta Pol Pharm
; 68(5): 665-75, 2011.
Artículo
en Inglés
| MEDLINE | ID: mdl-21928711
12.
Synthesis and Evaluation of Cytotoxic Activity of Certain Benzo[h]chromene Derivatives.
Anticancer Agents Med Chem
; 21(8): 963-986, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-32981512
13.
WITHDRAWN: Synthesis and biological evaluation of some novel Pyrrolo[2, 3-d]pyrimidine derivatives.
Bioorg Med Chem Lett
; 2010 Aug 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-20696577
14.
Synthesis of certain pyrimidine derivatives as antimicrobial agents and anti-inflammatory agents.
Molecules
; 15(3): 1882-90, 2010 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20336018
15.
Novel 3-(p-substituted phenyl)-6-bromo-4(3H)-quinazolinone derivatives of promising antiinflammatory and analgesic properties.
Acta Pol Pharm
; 66(5): 487-500, 2009.
Artículo
en Inglés
| MEDLINE | ID: mdl-19894645
16.
Evaluation of novel pyrrolopyrimidine derivatives as antiviral against gastroenteric viral infections.
Eur J Pharm Sci
; 127: 102-114, 2019 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30366078
17.
New anti-inflammatory agents.
Z Naturforsch C J Biosci
; 62(1-2): 27-31, 2007.
Artículo
en Inglés
| MEDLINE | ID: mdl-17425101
18.
Synthesis and Evaluation of Cytotoxic Activity of Some Pyrroles and Fused Pyrroles.
Anticancer Agents Med Chem
; 17(7): 1014-1025, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28042776
19.
Allosteric HIV-1 integrase inhibitors promote aberrant protein multimerization by directly mediating inter-subunit interactions: Structural and thermodynamic modeling studies.
Protein Sci
; 25(11): 1911-1917, 2016 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-27503276
20.
Synthesis and kinetic testing of tetrahydropyrimidine-2-thione and pyrrole derivatives as inhibitors of the metallo-ß-lactamase from Klebsiella pneumonia and Pseudomonas aeruginosa.
Chem Biol Drug Des
; 80(4): 500-15, 2012 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-22738437