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1.
A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding.
J Immunol
; 198(1): 528-537, 2017 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27881707
2.
Correction: A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding.
J Immunol
; 199(5): 1943, 2017 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28827388
3.
Innate TCRß-chain engagement drives human T cells toward distinct memory-like effector phenotypes with immunotherapeutic potentials.
Sci Adv
; 9(49): eadj6174, 2023 12 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-38055824
4.
A T cell receptor ß chain-directed antibody fusion molecule activates and expands subsets of T cells to promote antitumor activity.
Sci Transl Med
; 15(724): eadi0258, 2023 11 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-38019931
5.
Discovery of LYC-55716: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor-γ (RORγ) Agonist for Use in Treating Cancer.
J Med Chem
; 64(18): 13410-13428, 2021 09 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-34499493
6.
Preclinical investigations and a first-in-human phase I trial of M4112, the first dual inhibitor of indoleamine 2,3-dioxygenase 1 and tryptophan 2,3-dioxygenase 2, in patients with advanced solid tumors.
J Immunother Cancer
; 8(2)2020 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32843490
7.
Distinct role of MAPKAPK-2 in the regulation of TNF gene expression by Toll-like receptor 7 and 9 ligands.
Mol Immunol
; 44(14): 3482-91, 2007 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-17485113
8.
In Vitro Priming of Adoptively Transferred T Cells with a RORγ Agonist Confers Durable Memory and Stemness In Vivo.
Cancer Res
; 78(14): 3888-3898, 2018 07 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29769201
9.
Delayed cutaneous wound healing in mice lacking solute carrier 11a1 (formerly Nramp1): correlation with decreased expression of secretory leukocyte protease inhibitor.
J Invest Dermatol
; 126(4): 890-901, 2006 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-16470178
10.
Role of SLC11A1 (formerly NRAMP1) in regulation of signal transduction induced by Toll-like receptor 7 ligands.
FEMS Immunol Med Microbiol
; 47(1): 138-47, 2006 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-16706797
11.
A Novel IL6 Antibody Sensitizes Multiple Tumor Types to Chemotherapy Including Trastuzumab-Resistant Tumors.
Cancer Res
; 76(2): 480-90, 2016 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26744529
12.
Synthetic RORγ agonists regulate multiple pathways to enhance antitumor immunity.
Oncoimmunology
; 5(12): e1254854, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-28123897
13.
Whole-molecule antibody engineering: generation of a high-affinity anti-IL-6 antibody with extended pharmacokinetics.
J Mol Biol
; 411(4): 791-807, 2011 Aug 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-21723291
14.
Role of Ets-1 phosphorylation in the effector function of Th cells.
Eur J Immunol
; 38(6): 1700-5, 2008 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-18465773
15.
Ets-1 is a negative regulator of Th17 differentiation.
J Exp Med
; 204(12): 2825-35, 2007 Nov 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-17967903
16.
Chronic asthma-induced airway remodeling is prevented by toll-like receptor-7/8 ligand S28463.
Am J Respir Crit Care Med
; 175(12): 1241-9, 2007 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17400732
17.
Recombinant congenic strains of mice: a new tool for the genetic dissection of efficacy and toxicity of adjuvants.
Vaccine
; 21(9-10): 832-5, 2003 Feb 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-12547590
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