Detalles de la búsqueda
1.
The bacterial quorum sensing molecule, 2-heptyl-3-hydroxy-4-quinolone (PQS), inhibits signal transduction mechanisms in brain tissue and is behaviorally active in mice.
Pharmacol Res
; 170: 105691, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-34044128
2.
Comparative Effects of LY3020371, a Potent and Selective Metabotropic Glutamate (mGlu) 2/3 Receptor Antagonist, and Ketamine, a Noncompetitive N-Methyl-d-Aspartate Receptor Antagonist in Rodents: Evidence Supporting the Use of mGlu2/3 Antagonists, for the Treatment of Depression.
J Pharmacol Exp Ther
; 361(1): 68-86, 2017 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-28138040
3.
The Rapidly Acting Antidepressant Ketamine and the mGlu2/3 Receptor Antagonist LY341495 Rapidly Engage Dopaminergic Mood Circuits.
J Pharmacol Exp Ther
; 358(1): 71-82, 2016 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-27189960
4.
Preclinical predictors that the orthosteric mGlu2/3 receptor antagonist LY3020371 will not engender ketamine-associated neurotoxic, motor, cognitive, subjective, or abuse-liability-related effects.
Pharmacol Biochem Behav
; 155: 43-55, 2017 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-28285123
5.
Group II selective metabotropic glutamate receptor agonists and local cerebral glucose use in the rat.
J Cereb Blood Flow Metab
; 19(10): 1083-91, 1999 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-10532632
6.
Pharmacological agents acting at subtypes of metabotropic glutamate receptors.
Neuropharmacology
; 38(10): 1431-76, 1999 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-10530808
7.
1-BCP, a memory-enhancing agent, selectively potentiates AMPA-induced [3H]norepinephrine release in rat hippocampal slices.
Neuropharmacology
; 34(2): 141-7, 1995 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-7542369
8.
LY354740: a metabotropic glutamate receptor agonist which ameliorates symptoms of nicotine withdrawal in rats.
Neuropharmacology
; 36(11-12): 1511-6, 1997.
Artículo
en Inglés
| MEDLINE | ID: mdl-9517421
9.
Acute increases in monoamine release in the rat prefrontal cortex by the mGlu2/3 agonist LY379268 are similar in profile to risperidone, not locally mediated, and can be elicited in the presence of uptake blockade.
Neuropharmacology
; 40(7): 847-55, 2001 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-11378155
10.
Selective inhibition of forskolin-stimulated cyclic AMP formation in rat hippocampus by a novel mGluR agonist, 2R,4R-4-aminopyrrolidine-2,4- dicarboxylate.
Neuropharmacology
; 34(8): 843-50, 1995 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-8532165
11.
Specificity of phencyclidine-like drugs and benzomorphan opiates for two high affinity phencyclidine binding sites in guinea pig brain.
Neuropharmacology
; 29(9): 811-7, 1990 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-1963480
12.
The novel metabotropic glutamate receptor agonist 2R,4R-APDC potentiates stimulation of phosphoinositide hydrolysis in the rat hippocampus by 3,5-dihydroxyphenylglycine: evidence for a synergistic interaction between group 1 and group 2 receptors.
Neuropharmacology
; 35(12): 1661-72, 1996.
Artículo
en Inglés
| MEDLINE | ID: mdl-9076745
13.
Wash-resistant inhibition of phencyclidine- and haloperidol-sensitive sigma receptor sites in guinea pig brain by putative affinity ligands: determination of selectivity.
Neuropharmacology
; 29(11): 1047-53, 1990 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-1965013
14.
LY354740 is a potent and highly selective group II metabotropic glutamate receptor agonist in cells expressing human glutamate receptors.
Neuropharmacology
; 36(1): 1-11, 1997 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-9144636
15.
Synthesis and evaluation of 3-substituted analogues of 1,2,3,4-tetrahydroisoquinoline as inhibitors of phenylethanolamine N-methyltransferase.
J Med Chem
; 31(4): 824-30, 1988 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-3351861
16.
Conformational requirements of substrates for activity with phenylethanolamine N-methyltransferase.
J Med Chem
; 31(1): 169-71, 1988 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-3336016
17.
Conformational and steric aspects of the inhibition of phenylethanolamine N-methyltransferase by benzylamines.
J Med Chem
; 31(2): 433-44, 1988 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-3339613
18.
Conformational preference for the binding of biaryl substrates and inhibitors to the active site of phenylethanolamine N-methyltransferase.
J Med Chem
; 31(1): 60-5, 1988 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-3336033
19.
Probes of the active site of norepinephrine N-methyltransferase: effect of hydrophobic and hydrophilic interactions on side-chain binding of amphetamine and alpha-methylbenzylamine.
J Med Chem
; 25(10): 1248-50, 1982 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-7143366
20.
Synthesis and structure-activity relationship of C5-substituted analogues of (+-)-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine [(+-)-desmethyl-MK801]: ligands for the NMDA receptor-coupled phencyclidine binding site.
J Med Chem
; 33(3): 1069-76, 1990 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-2155320