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1.
The TBC1D31/praja2 complex controls primary ciliogenesis through PKA-directed OFD1 ubiquitylation.
EMBO J
; 40(10): e106503, 2021 05 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-33934390
2.
Ubiquitylation of BBSome is required for ciliary assembly and signaling.
EMBO Rep
; 24(4): e55571, 2023 04 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36744302
3.
Discovery of Bile Acid Derivatives as Potent ACE2 Activators by Virtual Screening and Essential Dynamics.
J Chem Inf Model
; 62(1): 196-209, 2022 01 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34914393
4.
Molecular Basis for Non-Covalent, Non-Competitive FAAH Inhibition.
Int J Mol Sci
; 23(24)2022 Dec 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-36555144
5.
Design, synthesis and in vitro and in vivo biological evaluation of flurbiprofen amides as new fatty acid amide hydrolase/cyclooxygenase-2 dual inhibitory potential analgesic agents.
J Enzyme Inhib Med Chem
; 36(1): 940-953, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-33896320
6.
Exploring the fatty acid amide hydrolase and cyclooxygenase inhibitory properties of novel amide derivatives of ibuprofen.
J Enzyme Inhib Med Chem
; 35(1): 815-823, 2020 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-32200655
7.
Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations.
Proc Natl Acad Sci U S A
; 114(11): E2136-E2145, 2017 03 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-28232513
8.
Multi-Targeting Bioactive Compounds Extracted from Essential Oils as Kinase Inhibitors.
Molecules
; 25(9)2020 May 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32384767
9.
Benzylamides and piperazinoarylamides of ibuprofen as fatty acid amide hydrolase inhibitors.
J Enzyme Inhib Med Chem
; 34(1): 562-576, 2019 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-30688118
10.
Identification of G-quadruplex DNA/RNA binders: Structure-based virtual screening and biophysical characterization.
Biochim Biophys Acta Gen Subj
; 1861(5 Pt B): 1329-1340, 2017 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-28025082
11.
Chemoinformatic Database Building and in Silico Hit-Identification of Potential Multi-Targeting Bioactive Compounds Extracted from Mushroom Species.
Molecules
; 22(9)2017 Sep 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-32961649
12.
Macrocyclic naphthalene diimides as G-quadruplex binders.
Bioorg Med Chem
; 23(13): 3819-30, 2015 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25935290
13.
Structure-based virtual screening of novel natural alkaloid derivatives as potential binders of h-telo and c-myc DNA G-quadruplex conformations.
Molecules
; 20(1): 206-23, 2014 Dec 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-25547724
14.
Exploring the DNA2-PNA heterotriplex formation in targeting the Bcl-2 gene promoter: A structural insight by physico-chemical and microsecond-scale MD investigation.
Heliyon
; 10(3): e24599, 2024 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38317891
15.
Bile acids serve as endogenous antagonists of the Leukemia inhibitory factor (LIF) receptor in oncogenesis.
Biochem Pharmacol
; 223: 116134, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38494064
16.
Molecular and Structural Aspects of Clinically Relevant Mutations of SARS-CoV-2 RNA-Dependent RNA Polymerase in Remdesivir-Treated Patients.
Pharmaceuticals (Basel)
; 16(8)2023 Aug 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37631058
17.
Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinoma.
Front Oncol
; 13: 1140730, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36998446
18.
The leukemia inhibitory factor regulates fibroblast growth factor receptor 4 transcription in gastric cancer.
Cell Oncol (Dordr)
; 2023 Nov 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37945798
19.
GRID-based three-dimensional pharmacophores II: PharmBench, a benchmark data set for evaluating pharmacophore elucidation methods.
J Chem Inf Model
; 52(10): 2599-608, 2012 Oct 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-22970854
20.
Chromene Derivatives as Selective TERRA G-Quadruplex RNA Binders with Antiproliferative Properties.
Pharmaceuticals (Basel)
; 15(5)2022 Apr 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-35631373