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1.
Allosteric Inhibition of SHP2 Stimulates Antitumor Immunity by Transforming the Immunosuppressive Environment.
Cancer Res
; 80(13): 2889-2902, 2020 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32350067
2.
RAS nucleotide cycling underlies the SHP2 phosphatase dependence of mutant BRAF-, NF1- and RAS-driven cancers.
Nat Cell Biol
; 20(9): 1064-1073, 2018 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-30104724
3.
FASN Inhibition and Taxane Treatment Combine to Enhance Anti-tumor Efficacy in Diverse Xenograft Tumor Models through Disruption of Tubulin Palmitoylation and Microtubule Organization and FASN Inhibition-Mediated Effects on Oncogenic Signaling and Gene Expression.
EBioMedicine
; 16: 51-62, 2017 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-28159572
4.
Inhibition of de novo Palmitate Synthesis by Fatty Acid Synthase Induces Apoptosis in Tumor Cells by Remodeling Cell Membranes, Inhibiting Signaling Pathways, and Reprogramming Gene Expression.
EBioMedicine
; 2(8): 808-24, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-26425687
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