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1.
Quantitative Analysis of mRNA and Protein Expression Levels of Aldo-Keto Reductase and Short-Chain Dehydrogenase/Reductase Isoforms in the Human Intestine.
Drug Metab Dispos
; 51(12): 1569-1577, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37722844
2.
Development and Validation of a Proteomic Correlation Profiling Technique to Detect and Identify Enzymes Involved in Metabolism of Drugs of Concern.
Drug Metab Dispos
; 51(7): 824-832, 2023 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-37156625
3.
Improvement of Protein Expression Profile in Three-Dimensional Renal Proximal Tubular Epithelial Cell Spheroids Selected Based on OAT1 Gene Expression: A Potential In Vitro Tool for Evaluating Human Renal Proximal Tubular Toxicity and Drug Disposition.
Drug Metab Dispos
; 51(9): 1177-1187, 2023 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37385755
4.
Characterization of Enzymes Involved in Nintedanib Metabolism in Humans.
Drug Metab Dispos
; 51(6): 733-742, 2023 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-36927840
5.
Identification of HSD17B12 as an enzyme catalyzing drug reduction reactions through investigation of nabumetone metabolism.
Arch Biochem Biophys
; 736: 109536, 2023 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36724833
6.
Regional Transcriptomics and Proteomics of Pharmacokinetics-Related Genes in Human Intestine.
Mol Pharm
; 20(6): 2876-2890, 2023 06 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37132462
7.
Quantitative Expression of Hepatobiliary Transporters and Functional Uptake of Substrates in Hepatic Two-Dimensional Sandwich Cultures: A Comparative Evaluation of Upcyte and Primary Human Hepatocytes.
Drug Metab Dispos
; 46(2): 166-177, 2018 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29212823
8.
Monolayer platform using human biopsy-derived duodenal organoids for pharmaceutical research.
Mol Ther Methods Clin Dev
; 22: 263-278, 2021 Sep 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34485610
9.
Modelling Torsade de Pointes arrhythmias in vitro in 3D human iPS cell-engineered heart tissue.
Nat Commun
; 8(1): 1078, 2017 10 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-29057872
10.
Effects of mutations of ABCA1 in the first extracellular domain on subcellular trafficking and ATP binding/hydrolysis.
J Biol Chem
; 278(10): 8815-9, 2003 Mar 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-12509412
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