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1.
Structural optimization and structure-functional selectivity relationship studies of G protein-biased EP2 receptor agonists.
Bioorg Med Chem Lett
; 26(10): 2446-2449, 2016 05 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27055938
2.
Curcumin Inhibits the proteinase-activated receptor-2-triggered prostaglandin E2 production by suppressing cyclooxygenase-2 upregulation and Akt-dependent activation of nuclear factor-κB in human lung epithelial cells.
J Pharmacol Sci
; 114(2): 225-9, 2010.
Artículo
en Inglés
| MEDLINE | ID: mdl-20838026
3.
Proteinase-activated receptor-2-triggered prostaglandin E(2) release, but not cyclooxygenase-2 upregulation, requires activation of the phosphatidylinositol 3-kinase/Akt / nuclear factor-kappaB pathway in human alveolar epithelial cells.
J Pharmacol Sci
; 111(3): 269-75, 2009 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-19881225
4.
Signal transduction for formation/release of interleukin-8 caused by a PAR2-activating peptide in human lung epithelial cells.
Regul Pept
; 145(1-3): 42-8, 2008 Jan 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-17854923
5.
Evidence that PAR2-triggered prostaglandin E2 (PGE2) formation involves the ERK-cytosolic phospholipase A2-COX-1-microsomal PGE synthase-1 cascade in human lung epithelial cells.
Cell Biochem Funct
; 26(2): 279-82, 2008.
Artículo
en Inglés
| MEDLINE | ID: mdl-17708577
6.
Discovery of G Protein-Biased EP2 Receptor Agonists.
ACS Med Chem Lett
; 7(3): 306-11, 2016 Mar 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-26985320
7.
EP300 Protects from Light-Induced Retinopathy in Zebrafish.
Front Pharmacol
; 7: 126, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27242532
8.
IOP-Lowering Effect of ONO-9054, A Novel Dual Agonist of Prostanoid EP3 and FP Receptors, in Monkeys.
Invest Ophthalmol Vis Sci
; 56(4): 2547-52, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25788650
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