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1.
Application of hepatic cytochrome b5/P450 reductase null (HBRN) mice to study the role of cytochrome b5 in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine.
Toxicol Appl Pharmacol
; 366: 64-74, 2019 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30685480
2.
Cytochrome b 5 impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b 5 /P450 reductase null (HBRN) mice.
Arch Toxicol
; 92(4): 1625-1638, 2018 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-29368147
3.
Impact of genetic modulation of SULT1A enzymes on DNA adduct formation by aristolochic acids and 3-nitrobenzanthrone.
Arch Toxicol
; 91(4): 1957-1975, 2017 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-27557898
4.
Effectiveness of human cytochrome P450 3A4 present in liposomal and microsomal nanoparticles in formation of covalent DNA adducts by ellipticine.
Neuro Endocrinol Lett
; 37(Suppl1): 95-102, 2016 Dec 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-28263536
5.
Preparation and application of anti-peptide antibodies for detection of orphan cytochromes P450.
Neuro Endocrinol Lett
; 36 Suppl 1: 38-45, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26757124
6.
The anticancer drug ellipticine activated with cytochrome P450 mediates DNA damage determining its pharmacological efficiencies: studies with rats, Hepatic Cytochrome P450 Reductase Null (HRN™) mice and pure enzymes.
Int J Mol Sci
; 16(1): 284-306, 2014 Dec 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-25547492
7.
The impact of chemotherapeutic drugs on the CYP1A1-catalysed metabolism of the environmental carcinogen benzo[a]pyrene: Effects in human colorectal HCT116 TP53(+/+), TP53(+/-) and TP53(-/-) cells.
Toxicology
; 398-399: 1-12, 2018 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29471073
8.
Heterologous expression of human cytochrome P450 2S1 in Escherichia coli and investigation of its role in metabolism of benzo[a]pyrene and ellipticine.
Monatsh Chem
; 147: 881-888, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27110039
9.
Induced expression of microsomal cytochrome b5 determined at mRNA and protein levels in rats exposed to ellipticine, benzo[a]pyrene, and 1-phenylazo-2-naphthol (Sudan I).
Monatsh Chem
; 147: 897-904, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27110040
10.
Pulmonary Inflammation Impacts on CYP1A1-Mediated Respiratory Tract DNA Damage Induced by the Carcinogenic Air Pollutant Benzo[a]pyrene.
Toxicol Sci
; 146(2): 213-25, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-25911668
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