Detalles de la búsqueda
1.
Reactivators of butyrylcholinesterase inhibited by organophosphorus compounds.
Bioorg Chem
; 150: 107526, 2024 Jun 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-38878749
2.
Brominated oxime nucleophiles are efficiently reactivating cholinesterases inhibited by nerve agents.
Arch Toxicol
; 2024 May 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-38789714
3.
Recent advances in dopamine D2 receptor ligands in the treatment of neuropsychiatric disorders.
Med Res Rev
; 43(1): 55-211, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36111795
4.
Physiologically relevant fluorescent assay for identification of 17ß-hydroxysteroid dehydrogenase type 10 inhibitors.
J Neurochem
; 167(2): 154-167, 2023 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-37458164
5.
Strategies for enhanced bioavailability of oxime reactivators in the central nervous system.
Arch Toxicol
; 97(11): 2839-2860, 2023 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37642747
6.
Cysteine conjugates of acetaminophen and p-aminophenol are potent inducers of cellular impairment in human proximal tubular kidney HK-2 cells.
Arch Toxicol
; 97(11): 2943-2954, 2023 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37639014
7.
Small-molecule inhibitors of cyclophilin D as potential therapeutics in mitochondria-related diseases.
Med Res Rev
; 42(5): 1822-1855, 2022 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35575048
8.
Charged pyridinium oximes with thiocarboxamide moiety are equally or less effective reactivators of organophosphate-inhibited cholinesterases compared to analogous carboxamides.
J Enzyme Inhib Med Chem
; 37(1): 760-767, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35193448
9.
Hypothesis: JNK signaling is a therapeutic target of neurodegenerative diseases.
Alzheimers Dement
; 18(1): 152-158, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34032377
10.
Effects of Charged Oxime Reactivators on the HK-2 Cell Line in Renal Toxicity Screening.
Chem Res Toxicol
; 34(3): 699-703, 2021 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33566584
11.
Tacrine - Benzothiazoles: Novel class of potential multitarget anti-Alzheimers drugs dealing with cholinergic, amyloid and mitochondrial systems.
Bioorg Chem
; 107: 104596, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33421953
12.
Development of versatile and potent monoquaternary reactivators of acetylcholinesterase.
Arch Toxicol
; 95(3): 985-1001, 2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33517499
13.
Pyridinium-2-carbaldoximes with quinolinium carboxamide moiety are simultaneous reactivators of acetylcholinesterase and butyrylcholinesterase inhibited by nerve agent surrogates.
J Enzyme Inhib Med Chem
; 36(1): 437-449, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-33467931
14.
Design, synthesis, and in vitro evaluation of BP-1-102 analogs with modified hydrophobic fragments for STAT3 inhibition.
J Enzyme Inhib Med Chem
; 36(1): 410-424, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-33440995
15.
Conifers Phytochemicals: A Valuable Forest with Therapeutic Potential.
Molecules
; 26(10)2021 May 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-34070179
16.
Recent advances with 5-HT3 modulators for neuropsychiatric and gastrointestinal disorders.
Med Res Rev
; 40(5): 1593-1678, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32115745
17.
RNase T1 Refolding Assay for Determining Mitochondrial Cyclophilin D Activity: A Novel In Vitro Method Applicable in Drug Research and Discovery.
Biochemistry
; 59(17): 1680-1687, 2020 05 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-32275395
18.
Friend or enemy? Review of 17ß-HSD10 and its role in human health or disease.
J Neurochem
; 155(3): 231-249, 2020 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-32306391
19.
An update on T-2 toxin and its modified forms: metabolism, immunotoxicity mechanism, and human exposure assessment.
Arch Toxicol
; 94(11): 3645-3669, 2020 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-32910237
20.
1,2,4-Triazole-based anticonvulsant agents with additional ROS scavenging activity are effective in a model of pharmacoresistant epilepsy.
J Enzyme Inhib Med Chem
; 35(1): 993-1002, 2020 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-32253957