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1.
Synthesis and antiviral evaluation of a novel series of homoserine-based inhibitors of the hepatitis C virus NS3/4A serine protease.
Bioorg Med Chem Lett
; 25(18): 3984-91, 2015 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26231161
2.
Structure-based design of a novel series of azetidine inhibitors of the hepatitis C virus NS3/4A serine protease.
Bioorg Med Chem Lett
; 24(18): 4444-4449, 2014 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25155387
3.
Cellular collusion: cracking the code of immunosuppression and chemo resistance in PDAC.
Front Immunol
; 15: 1341079, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38817612
4.
Immune checkpoint blockade therapy mitigates systemic inflammation and affects cellular FLIP-expressing monocytic myeloid-derived suppressor cells in non-progressor non-small cell lung cancer patients.
Oncoimmunology
; 12(1): 2253644, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37720688
5.
Fatal cytokine release syndrome by an aberrant FLIP/STAT3 axis.
Cell Death Differ
; 29(2): 420-438, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34518653
6.
Interrupting the nitrosative stress fuels tumor-specific cytotoxic T lymphocytes in pancreatic cancer.
J Immunother Cancer
; 10(1)2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35022194
7.
Phenotypical Characterization and Isolation of Tumor-Derived Mouse Myeloid-Derived Suppressor Cells.
Methods Mol Biol
; 2236: 29-42, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-33237538
8.
A Complex Metabolic Network Confers Immunosuppressive Functions to Myeloid-Derived Suppressor Cells (MDSCs) within the Tumour Microenvironment.
Cells
; 10(10)2021 10 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34685679
9.
Immunization against ROS1 by DNA Electroporation Impairs K-Ras-Driven Lung Adenocarcinomas â.
Vaccines (Basel)
; 8(2)2020 Apr 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32268572
10.
Baricitinib restrains the immune dysregulation in patients with severe COVID-19.
J Clin Invest
; 130(12): 6409-6416, 2020 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32809969
11.
Synthesis and antiviral evaluation of thieno[3,4-d]pyrimidine C-nucleoside analogues of 2',3'-dideoxy- and 2',3'-dideoxy-2',3'-didehydro-adenosine and -inosine.
Bioorg Med Chem
; 17(6): 2321-6, 2009 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19254848
12.
2'-C-Methyl branched pyrimidine ribonucleoside analogues: potent inhibitors of RNA virus replication.
Antivir Chem Chemother
; 18(4): 225-42, 2007.
Artículo
en Inglés
| MEDLINE | ID: mdl-17907380
13.
Discovery of the Aryl-phospho-indole IDX899, a Highly Potent Anti-HIV Non-nucleoside Reverse Transcriptase Inhibitor.
J Med Chem
; 59(5): 1891-8, 2016 Mar 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-26804933
14.
Design, synthesis and antiviral evaluation of 2'-C-methyl branched guanosine pronucleotides: the discovery of IDX184, a potent liver-targeted HCV polymerase inhibitor.
Future Med Chem
; 7(13): 1675-700, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26424162
15.
Computer-aided design, synthesis, and anti-HIV-1 activity in vitro of 2-alkylamino-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as novel potent non-nucleoside reverse transcriptase inhibitors, also active against the Y181C variant.
J Med Chem
; 47(4): 928-34, 2004 Feb 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-14761194
16.
Pyrrolo[1,2-f]phenanthridines and related non-rigid analogues as antiviral agents.
Eur J Med Chem
; 37(1): 3-10, 2002 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-11841870
17.
Synthesis and biological evaluation of aryl-phospho-indole as novel HIV-1 non-nucleoside reverse transcriptase inhibitors.
J Med Chem
; 54(1): 392-5, 2011 Jan 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-21142105
18.
Synthesis and antiviral evaluation of a seven-membered sugar ring nucleoside analog, 9-(5-deoxy-beta-D-allo-septanosyl)-adenine.
Nucleic Acids Symp Ser (Oxf)
; (52): 611-2, 2008.
Artículo
en Inglés
| MEDLINE | ID: mdl-18776528
19.
5-Alkyl-2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4-dihydropyrimidin-4(3H)-ones, a new series of potent, broad-spectrum non-nucleoside reverse transcriptase inhibitors belonging to the DABO family.
Bioorg Med Chem
; 13(6): 2065-77, 2005 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-15727860
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