Detalles de la búsqueda
1.
Inhibition of follicle-stimulating hormone-induced preovulatory follicles in rats treated with a nonsteroidal negative allosteric modulator of follicle-stimulating hormone receptor.
Biol Reprod
; 90(1): 19, 2014 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-24285717
2.
The mGluR5 negative allosteric modulator dipraglurant reduces dyskinesia in the MPTP macaque model.
Mov Disord
; 29(8): 1074-9, 2014 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-24865335
3.
ADX71743, a potent and selective negative allosteric modulator of metabotropic glutamate receptor 7: in vitro and in vivo characterization.
J Pharmacol Exp Ther
; 344(3): 624-36, 2013 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-23257312
4.
Effect of the Metabotropic Glutamate Receptor Type 5 Negative Allosteric Modulator Dipraglurant on Motor and Non-Motor Symptoms of Parkinson's Disease.
Cells
; 12(7)2023 03 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-37048075
5.
Lateral allosterism in the glucagon receptor family: glucagon-like peptide 1 induces G-protein-coupled receptor heteromer formation.
Mol Pharmacol
; 81(3): 309-18, 2012 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-22108912
6.
Fluorinated 9H-xanthene-9-carboxylic acid oxazol-2-yl-amides as potent, orally available mGlu1 receptor enhancers.
Bioorg Med Chem Lett
; 19(6): 1666-9, 2009 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19233648
7.
Synthesis and characterization of 8-ethynyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one derivatives: part 2. New potent non-competitive metabotropic glutamate receptor 2/3 antagonists.
Bioorg Med Chem Lett
; 18(3): 1091-5, 2008 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18096387
8.
Synthesis and characterization of 1,3-dihydro-benzo[b][1,4]diazepin-2-one derivatives: Part 3. New potent non-competitive metabotropic glutamate receptor 2/3 antagonists.
Bioorg Med Chem Lett
; 18(8): 2725-9, 2008 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18374569
9.
Cellular prion protein signaling in serotonergic neuronal cells.
Ann N Y Acad Sci
; 1096: 106-19, 2007 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-17405922
10.
Synthesis and characterization of 8-ethynyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one derivatives: new potent non-competitive metabotropic glutamate receptor 2/3 antagonists. Part 1.
Bioorg Med Chem Lett
; 17(24): 6811-5, 2007 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17964783
11.
The drug candidate, ADX71441, is a novel, potent and selective positive allosteric modulator of the GABAB receptor with a potential for treatment of anxiety, pain and spasticity.
Neuropharmacology
; 114: 34-47, 2017 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27889489
12.
Control of bioamine metabolism by 5-HT2B and alpha 1D autoreceptors through reactive oxygen species and tumor necrosis factor-alpha signaling in neuronal cells.
Ann N Y Acad Sci
; 1091: 123-41, 2006 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-17341609
13.
Reactive oxygen species-dependent TNF-alpha converting enzyme activation through stimulation of 5-HT2B and alpha1D autoreceptors in neuronal cells.
FASEB J
; 19(9): 1078-87, 2005 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-15985531
14.
Severe impairment of NMDA receptor function in mice carrying targeted point mutations in the glycine binding site results in drug-resistant nonhabituating hyperactivity.
J Neurosci
; 22(15): 6713-23, 2002 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-12151550
15.
Distribution and abundance of metabotropic glutamate receptor subtype 2 in rat brain revealed by [3H]LY354740 binding in vitro and quantitative radioautography: correlation with the sites of synthesis, expression, and agonist stimulation of [35S]GTPgammas binding.
J Comp Neurol
; 487(1): 15-27, 2005 Jun 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-15861463
16.
Differential regulation of synaptic transmission by mGlu2 and mGlu3 at the perforant path inputs to the dentate gyrus and CA1 revealed in mGlu2 -/- mice.
Neuropharmacology
; 43(2): 215-21, 2002 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-12213275
17.
Pharmacological manipulation of mGlu2 receptors influences cognitive performance in the rodent.
Neuropharmacology
; 46(7): 907-17, 2004 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-15081787
18.
Identification and characterization of a novel splice variant of the metabotropic glutamate receptor 5 gene in human hippocampus and cerebellum.
Brain Res Mol Brain Res
; 109(1-2): 168-78, 2002 Dec 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-12531526
19.
Alkyl diphenylacetyl, 9H-xanthene- and 9H-thioxanthene-carbonyl carbamates as positive allosteric modulators of mGlu1 receptors.
Farmaco
; 57(12): 989-92, 2002 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-12564473
20.
The pros of not being competitive.
Curr Neuropharmacol
; 5(3): 148, 2007 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-19305796