Detalles de la búsqueda
1.
Molecular hybrids of substituted phenylcarbamoylpiperidine and 1,2,4-triazole methylacetamide as potent 15-LOX inhibitors: Design, synthesis, DFT calculations and molecular docking studies.
Bioorg Chem
; 143: 106984, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-38056389
2.
Assessing p-tolyloxy-1,3,4-oxadiazole acetamides as lipoxygenase inhibitors assisted by in vitro and in silico studies.
Bioorg Chem
; 129: 106144, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-36116325
3.
Exploring phenylcarbamoylazinane-1,2,4-triazole thioethers as lipoxygenase inhibitors supported with in vitro, in silico and cytotoxic studies.
Bioorg Chem
; 115: 105261, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34416506
4.
Identification of phenylcarbamoylazinane-1,3,4-oxadiazole amides as lipoxygenase inhibitors with expression analysis and in silico studies.
Bioorg Chem
; 115: 105243, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34403937
5.
Probing phenylcarbamoylazinane-1,2,4-triazole amides derivatives as lipoxygenase inhibitors along with cytotoxic, ADME and molecular docking studies.
Bioorg Chem
; 107: 104525, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33317840
6.
Targeting new N-furfurylated 4-chlorophenyl-1,2,4-triazolepropionamide hybrids as potential 15-lipoxygenase inhibitors supported with in vitro and in silico studies.
J Biomol Struct Dyn
; 41(11): 5166-5182, 2023 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35699270
7.
NADPH oxidase 4 mediates upregulation of type 4 phosphodiesterases in human endothelial cells.
J Cell Physiol
; 227(5): 1941-50, 2012 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-21732365
8.
4-Chlorophenyl-N-furfuryl-1,2,4-triazole Methylacetamides as Significant 15-Lipoxygenase Inhibitors: an Efficient Approach for Finding Lead Anti-inflammatory Compounds.
ACS Omega
; 7(23): 19721-19734, 2022 Jun 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-35721976
9.
The effect of 24-week belimumab treatment withdrawal followed by treatment restart in patients with SLE: an open-label, non-randomised 52-week study.
Arthritis Res Ther
; 24(1): 46, 2022 02 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-35172878
10.
Exogenous hydrogen sulfide inhibits superoxide formation, NOX-1 expression and Rac1 activity in human vascular smooth muscle cells.
J Vasc Res
; 45(6): 521-8, 2008.
Artículo
en Inglés
| MEDLINE | ID: mdl-18463417
11.
Superoxide auto-augments superoxide formation and upregulates gp91(phox) expression in porcine pulmonary artery endothelial cells: inhibition by iloprost.
Eur J Pharmacol
; 538(1-3): 108-14, 2006 May 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-16647052
12.
Nicotinamide adenine dinucleotide phosphate oxidase: a promiscuous therapeutic target for cardiovascular drugs?
Trends Cardiovasc Med
; 15(8): 278-82, 2005 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-16297764
13.
Nitroaspirins and morpholinosydnonimine but not aspirin inhibit the formation of superoxide and the expression of gp91phox induced by endotoxin and cytokines in pig pulmonary artery vascular smooth muscle cells and endothelial cells.
Circulation
; 110(9): 1140-7, 2004 Aug 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-15326075
14.
Prednisolone augments superoxide formation in porcine pulmonary artery endothelial cells through differential effects on the expression of nitric oxide synthase and NADPH oxidase.
Br J Pharmacol
; 145(5): 688-97, 2005 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-15852033
15.
Sildenafil citrate and sildenafil nitrate (NCX 911) are potent inhibitors of superoxide formation and gp91phox expression in porcine pulmonary artery endothelial cells.
Br J Pharmacol
; 146(1): 109-17, 2005 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-15980872
16.
Iloprost inhibits superoxide formation and gp91phox expression induced by the thromboxane A2 analogue U46619, 8-isoprostane F2alpha, prostaglandin F2alpha, cytokines and endotoxin in the pig pulmonary artery.
Br J Pharmacol
; 141(3): 488-96, 2004 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-14718263
17.
Reactive oxygen species, vascular disease and cardiovascular surgery.
Curr Vasc Pharmacol
; 2(3): 229-36, 2004 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-15320821
18.
NADPH oxidase 1 mediates upregulation of thromboxane A2 synthase in human vascular smooth muscle cells: inhibition with iloprost.
Eur J Pharmacol
; 658(2-3): 187-92, 2011 May 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-21371456
19.
Sexual dysfunction and cardiac risk (the second Princeton Concensus Conference).
Am J Cardiol
; 96(12): 1754-5, 2005 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-16360373
20.
Inhaled prostacyclin is safe, effective, and affordable in patients with pulmonary hypertension, right-heart dysfunction, and refractory hypoxemia after cardiothoracic surgery.
J Thorac Cardiovasc Surg
; 128(6): 949-50, 2004 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-15573083