Detalles de la búsqueda
1.
Endocrine disruption screening by protein and gene expression of vitellogenin in freshly isolated and cryopreserved rainbow trout hepatocytes.
Chem Res Toxicol
; 27(8): 1450-7, 2014 Aug 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-25055050
2.
Intra- and interlaboratory reliability of a cryopreserved trout hepatocyte assay for the prediction of chemical bioaccumulation potential.
Environ Sci Technol
; 48(14): 8170-8, 2014 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24941452
3.
Key learnings from performance of the U.S. EPA Endocrine Disruptor Screening Program (EDSP) Tier 1 in vitro assays.
Birth Defects Res B Dev Reprod Toxicol
; 101(1): 23-42, 2014 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-24515815
4.
Renal elimination of perfluorocarboxylates (PFCAs).
Chem Res Toxicol
; 25(1): 35-46, 2012 Jan 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-21985250
5.
Comparative metabolism of 1,2,3,3,3-pentafluoropropene in male and female mouse, rat, dog, and human liver microsomes and cytosol and male rat hepatocytes via oxidative dehalogenation and glutathione S-conjugation pathways.
Drug Metab Dispos
; 39(7): 1288-93, 2011 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-21493824
6.
Non-coplanar 2,2',3,3',4,4',5,5',6,6'-decachlorobiphenyl (PCB 209) did not induce cytochrome P450 enzyme activities in primary cultured rat hepatocytes, was not genotoxic, and did not exhibit endocrine-modulating activities.
Toxicology
; 255(3): 177-86, 2009 Jan 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-19022331
7.
Two-day inhalation toxicity study of methyl iodide in the rat.
Inhal Toxicol
; 21(6): 480-7, 2009 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-19519148
8.
Liver microsomes and S9 from rainbow trout (Oncorhynchus mykiss): comparison of basal-level enzyme activities with rat and determination of xenobiotic intrinsic clearance in support of bioaccumulation assessment.
Environ Toxicol Chem
; 28(3): 481-8, 2009 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-18937539
9.
Uptake of perfluorooctanoate in freshly isolated hepatocytes from male and female rats.
Toxicol Lett
; 181(2): 81-6, 2008 Sep 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-18662756
10.
Xenobiotic intrinsic clearance in freshly isolated hepatocytes from rainbow trout (Oncorhynchus mykiss): determination of trout hepatocellularity, optimization of cell concentrations and comparison of serum and serum-free incubations.
Aquat Toxicol
; 89(1): 11-7, 2008 Aug 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-18599132
11.
In vitro metabolism of 8-2 fluorotelomer alcohol: interspecies comparisons and metabolic pathway refinement.
Toxicol Sci
; 100(2): 333-44, 2007 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-17785680
12.
Primary culture of rat hepatocytes in 96-well plates: effects of extracellular matrix configuration on cytochrome P450 enzyme activity and inducibility, and its application in in vitro cytotoxicity screening.
Toxicol In Vitro
; 21(1): 165-73, 2007 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-17141466
13.
Comparison of basal level metabolic enzyme activities of freshly isolated hepatocytes from rainbow trout (Oncorhynchus mykiss) and rat.
Aquat Toxicol
; 80(1): 52-9, 2006 Oct 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-16935359
14.
Absorption, distribution, metabolism, excretion, and kinetics of 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid ammonium salt following a single dose in rat, mouse, and cynomolgus monkey.
Toxicology
; 340: 1-9, 2016 Jan 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-26743852
15.
Determination of Metabolic Stability Using Cryopreserved Hepatocytes from Rainbow Trout (Oncorhynchus mykiss).
Curr Protoc Toxicol
; 65: 4.42.1-4.42.29, 2015 Aug 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-26250400
16.
Aquatic hazard, bioaccumulation and screening risk assessment for 6:2 fluorotelomer sulfonate.
Chemosphere
; 128: 258-65, 2015 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-25725394
17.
Absorption, distribution, metabolism, and excretion of [1-¹4C]-perfluorohexanoate ([¹4C]-PFHx) in rats and mice.
Toxicology
; 283(1): 55-62, 2011 Apr 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-21349313
18.
Cryopreserved hepatocytes from rainbow trout (Oncorhynchus mykiss): a validation study to support their application in bioaccumulation assessment.
Environ Sci Technol
; 44(8): 3052-8, 2010 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20196591
19.
Kinetics of 8-2 fluorotelomer alcohol and its metabolites, and liver glutathione status following daily oral dosing for 45 days in male and female rats.
Chem Biol Interact
; 180(2): 281-95, 2009 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19497427
20.
Determination of xenobiotic intrinsic clearance in freshly isolated hepatocytes from rainbow trout (Oncorhynchus mykiss) and rat and its application in bioaccumulation assessment.
Environ Sci Technol
; 41(9): 3269-76, 2007 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-17539536