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1.
Impact of P-Glycoprotein-Mediated Active Efflux on Drug Distribution into Lumbar Cerebrospinal Fluid in Nonhuman Primates.
Drug Metab Dispos
; 48(11): 1183-1190, 2020 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-32862147
2.
Species difference in the mechanism of nonlinear pharmacokinetics of E2074, a novel sodium channel inhibitor, in rats, dogs, and monkeys.
Drug Metab Dispos
; 41(5): 1004-11, 2013 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-23401471
3.
Analysis of phosphorylated peptides by double pseudoneutral loss extraction coupled with derivatization using N-(4-bromobenzoyl)aminoethanethiol.
Anal Chem
; 81(22): 9395-401, 2009 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19845345
4.
Quantitative prediction of histamine H1 receptor occupancy by the sedative and non-sedative antagonists in the human central nervous system based on systemic exposure and preclinical data.
Drug Metab Pharmacokinet
; 32(2): 135-144, 2017 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-28190755
5.
Investigation of utility of cerebrospinal fluid drug concentration as a surrogate for interstitial fluid concentration using microdialysis coupled with cisternal cerebrospinal fluid sampling in wild-type and Mdr1a(-/-) rats.
Drug Metab Pharmacokinet
; 31(1): 57-66, 2016 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-26830080
6.
Pharmacodynamic and pharmacokinetic interactions of perampanel and other antiepileptic drugs in a rat amygdala kindling model.
Seizure
; 23(9): 732-9, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-24997072
7.
Utility of cerebrospinal fluid drug concentration as a surrogate for unbound brain concentration in nonhuman primates.
Drug Metab Pharmacokinet
; 29(5): 419-26, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24806821
8.
Corrigendum to "Quantitative prediction of histamine H1 receptor occupancy by the sedative and non-sedative antagonists in the human central nervous system based on systemic exposure and preclinical data" [Drug Metab Pharmacokinet 32 (2017) 135-144].
Drug Metab Pharmacokinet
; 32(4): 228, 2017 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-28587746
9.
Analysis of the antigen binding site of anti-deoxycholate monoclonal antibody using a novel affinity labeling reagent, acyl adenylate.
Biochemistry
; 43(7): 2041-8, 2004 Feb 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-14967044
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