Detalles de la búsqueda
1.
Enzymatic syntheses of novel carbocyclic scaffolds with a 6,5 + 5,5 ring system by squalene-hopene cyclase.
Org Biomol Chem
; 17(42): 9375-9389, 2019 10 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-31621743
2.
Strictly Conserved Residues in Euphorbia tirucalli ß-Amyrin Cyclase: Trp612 Stabilizes Transient Cation through Cation-π Interaction and CH-π Interaction of Tyr736 with Leu734 Confers Robust Local Protein Architecture.
Chembiochem
; 19(5): 486-495, 2018 03 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29214725
3.
Identification of a new diterpene biosynthetic gene cluster that produces O-methylkolavelool in Herpetosiphon aurantiacus.
Chembiochem
; 16(5): 772-81, 2015 Mar 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-25694050
4.
Structure and inhibition of tuberculosinol synthase and decaprenyl diphosphate synthase from Mycobacterium tuberculosis.
J Am Chem Soc
; 136(7): 2892-6, 2014 Feb 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-24475925
5.
ß-Amyrin synthase from Euphorbia tirucalli. Steric bulk, not the π-electrons of Phe, at position 474 has a key role in affording the correct folding of the substrate to complete the normal polycyclization cascade.
Org Biomol Chem
; 12(23): 3836-46, 2014 Jun 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-24695673
6.
Identification of novel sesterterpene/triterpene synthase from Bacillus clausii.
Chembiochem
; 14(7): 822-5, 2013 May 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-23554321
7.
The O-methyltransferase SrsB catalyzes the decarboxylative methylation of alkylresorcylic acid during phenolic lipid biosynthesis by Streptomyces griseus.
J Bacteriol
; 194(6): 1544-51, 2012 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-22247507
8.
Characterization of a novel sesquiterpene cyclase involved in (+)-caryolan-1-ol biosynthesis in Streptomyces griseus.
J Biol Chem
; 286(32): 27980-7, 2011 Aug 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-21693706
9.
Genome mining reveals two novel bacterial sesquiterpene cyclases: (-)-germacradien-4-ol and (-)-epi-α-bisabolol synthases from Streptomyces citricolor.
Chembiochem
; 12(15): 2271-5, 2011 Oct 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-23106076
10.
Substrate specificity of Rv3378c, an enzyme from Mycobacterium tuberculosis, and the inhibitory activity of the bicyclic diterpenoids against macrophage phagocytosis.
Org Biomol Chem
; 9(7): 2156-65, 2011 Apr 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-21290071
11.
Characterization of the Rv3378c gene product, a new diterpene synthase for producing tuberculosinol and (13R, S)-isotuberculosinol (nosyberkol), from the Mycobacterium tuberculosis H37Rv genome.
Biosci Biotechnol Biochem
; 75(1): 75-81, 2011.
Artículo
en Inglés
| MEDLINE | ID: mdl-21228491
12.
Biosynthesis of aliphatic polyketides by type III polyketide synthase and methyltransferase in Bacillus subtilis.
J Bacteriol
; 191(15): 4916-23, 2009 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-19465653
13.
Characterization of the Rv3377c gene product, a type-B diterpene cyclase, from the Mycobacterium tuberculosis H37 genome.
Chembiochem
; 10(12): 2060-71, 2009 Aug 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-19618417
14.
Identification of diterpene biosynthetic gene clusters and functional analysis of labdane-related diterpene cyclases in Phomopsis amygdali.
Biosci Biotechnol Biochem
; 72(4): 1038-47, 2008 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-18391465
15.
Identification of the first bacterial monoterpene cyclase, a 1,8-cineole synthase, that catalyzes the direct conversion of geranyl diphosphate.
Chembiochem
; 12(13): 1988-91, 2011 Sep 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-21726035
16.
Identification and characterization of the linalool/nerolidol synthase from Streptomyces clavuligerus.
Chembiochem
; 12(16): 2403-7, 2011 Nov 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-21910204
17.
Further Insight into Polycyclization Cascades of Acyclic Geranylfarnesol and its Acetate by Squalene-hopene Cyclase from Alicyclobacillus acidocaldarius.
Nat Prod Commun
; 11(2): 163-7, 2016 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-27032191
18.
Mycobacterium tuberculosis H37Rv3377c encodes the diterpene cyclase for producing the halimane skeleton.
Chem Commun (Camb)
; (8): 1016-8, 2005 Feb 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-15719101
19.
Biochemical characterization of the water-soluble squalene synthase from Methylococcus capsulatus and the functional analyses of its two DXXD(E)D motifs and the highly conserved aromatic amino acid residues.
FEBS J
; 281(24): 5479-97, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25283713
20.
Structure, function and inhibition of ent-kaurene synthase from Bradyrhizobium japonicum.
Sci Rep
; 4: 6214, 2014 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25269599