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1.
Generation and selection of novel fully human monoclonal antibodies that neutralize Dickkopf-1 (DKK1) inhibitory function in vitro and increase bone mass in vivo.
J Biol Chem
; 285(51): 40135-47, 2010 Dec 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-20929859
2.
Discovery of the selective androgen receptor modulator MK-0773 using a rational development strategy based on differential transcriptional requirements for androgenic anabolism versus reproductive physiology.
J Biol Chem
; 285(22): 17054-64, 2010 May 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-20356837
3.
A rate-limiting role for Dickkopf-1 in bone formation and the remediation of bone loss in mouse and primate models of postmenopausal osteoporosis by an experimental therapeutic antibody.
J Pharmacol Exp Ther
; 338(2): 568-78, 2011 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-21531794
4.
Identification of anabolic selective androgen receptor modulators with reduced activities in reproductive tissues and sebaceous glands.
J Biol Chem
; 284(52): 36367-36376, 2009 Dec 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-19846549
5.
A regulatory circuit mediating convergence between Nurr1 transcriptional regulation and Wnt signaling.
Mol Cell Biol
; 27(21): 7486-96, 2007 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-17709391
6.
Gene expression analyses in cynomolgus monkeys provides mechanistic insight into high-density lipoprotein-cholesterol reduction by androgens in primates.
Endocrinology
; 149(4): 1551-61, 2008 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-18187556
7.
Androgenic induction of growth and differentiation in the rodent uterus involves the modulation of estrogen-regulated genetic pathways.
Endocrinology
; 146(2): 564-78, 2005 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-15498879
8.
Androgen-mediated improvement of body composition and muscle function involves a novel early transcriptional program including IGF1, mechano growth factor, and induction of {beta}-catenin.
J Mol Endocrinol
; 44(1): 55-73, 2010 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-19726620
9.
Control of rat tail skin temperature regulation by estrogen receptor-beta selective ligand.
Maturitas
; 64(1): 46-51, 2009 Sep 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-19679413
10.
Design, synthesis, and biological evaluation of 16-substituted 4-azasteroids as tissue-selective androgen receptor modulators (SARMs).
J Med Chem
; 52(15): 4578-81, 2009 Aug 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-19606870
11.
Identification of genetic pathways activated by the androgen receptor during the induction of proliferation in the ventral prostate gland.
J Biol Chem
; 279(2): 1310-22, 2004 Jan 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-14576152
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