Búsqueda | Biblioteca Virtual en Salud

1.

Identification and optimisation of novel sulfonamide, selective vasopressin V1B receptor antagonists.

Baker, James; Bingham, Matilda; Blackburn-Munro, Ruth; Cai, Jiaqiang; Craighead, Mark; Gilfillan, Robert; Goan, Kate; Jaap, David; Milne, Rachel; Morphy, J Richard; Napier, Susan; Presland, Jeremy; Spinks, Gayle; Thomson, Fiona.

Bioorg Med Chem Lett ; 21(12): 3603-7, 2011 Jun 15.

Artículo en Inglés | MEDLINE | ID: mdl-21601454

2.

The identification, and optimisation of hERG selectivity, of a mixed NET/SERT re-uptake inhibitor for the treatment of pain.

Angus, Derek; Bingham, Matilda; Buchanan, Dawn; Dunbar, Neil; Gibson, Linsday; Goodwin, Richard; Haunsø, Anders; Houghton, Andrea; Huggett, Margaret; Morphy, Richard; Napier, Susan; Nimz, Olaf; Passmore, Joanna; Walker, Glenn.

Bioorg Med Chem Lett ; 21(1): 271-5, 2011 Jan 01.

Artículo en Inglés | MEDLINE | ID: mdl-21112782

3.

Optimisation of pharmacokinetic properties to afford an orally bioavailable and selective V1A receptor antagonist.

Arbuckle, William; Baker, James; Barn, David; Bingham, Matilda; Brown, Angus; Buchanan, Kirsteen; Craighead, Mark; Goodwin, Richard; Goutcher, Susan; Kiczun, Michael; Lyons, Amanda; Milne, Rachel; Montgomery, Brian; Napier, Susan; Presland, Jeremy; Sloan, Hazel; Turnbull, Zara; Wishart, Grant.

Bioorg Med Chem Lett ; 21(15): 4622-8, 2011 Aug 01.

Artículo en Inglés | MEDLINE | ID: mdl-21700453

4.

Synthesis and SAR studies of novel 2-(6-aminomethylaryl-2-aryl-4-oxo-quinazolin-3(4H)-yl)acetamide vasopressin V1b receptor antagonists.

Napier, Susan E; Letourneau, Jeffrey J; Ansari, Nasrin; Auld, Douglas S; Baker, James; Best, Stuart; Campbell-Wan, Leigh; Chan, Ray; Craighead, Mark; Desai, Hema; Ho, Koc-Kan; MacSweeney, Cliona; Milne, Rachel; Richard Morphy, J; Neagu, Irina; Ohlmeyer, Michael H J; Pick, Jack; Presland, Jeremy; Riviello, Chris; Zanetakos, Heather A; Zhao, Jiuqiao; Webb, Maria L.

Bioorg Med Chem Lett ; 21(12): 3813-7, 2011 Jun 15.

Artículo en Inglés | MEDLINE | ID: mdl-21596563

5.

The discovery of novel 8-azabicyclo[3.2.1]octan-3-yl)-3-(4-chlorophenyl) propanamides as vasopressin V1A receptor antagonists.

Napier, Susan; Wishart, Grant; Arbuckle, William; Baker, James; Barn, David; Bingham, Matilda; Brown, Angus; Byford, Alan; Claxton, Chris; Craighead, Mark; Buchanan, Kirsteen; Fielding, Lee; Gibson, Lindsay; Goodwin, Richard; Goutcher, Susan; Irving, Nicholas; MacSweeney, Cliona; Milne, Rachel; Mort, Chris; Presland, Jeremy; Sloan, Hazel; Thomson, Fiona; Turnbull, Zara; Young, Trevor.

Bioorg Med Chem Lett ; 21(10): 3163-7, 2011 May 15.

Artículo en Inglés | MEDLINE | ID: mdl-21458261

6.

Synthesis and SAR studies of novel 2-(4-oxo-2-aryl-quinazolin-3(4H)-yl)acetamide vasopressin V1b receptor antagonists.

Napier, Susan E; Letourneau, Jeffrey J; Ansari, Nasrin; Auld, Douglas S; Baker, James; Best, Stuart; Campbell-Wan, Leigh; Chan, Jui-Hsiang; Craighead, Mark; Desai, Hema; Goan, Katharine A; Ho, Koc-Kan; Hulskotte, Ellen G J; MacSweeney, Cliona P; Milne, Rachel; Morphy, J Richard; Neagu, Irina; Ohlmeyer, Michael H J; Peeters, Ard W M M; Presland, Jeremy; Riviello, Chris; Ruigt, Ge S F; Thomson, Fiona J; Zanetakos, Heather A; Zhao, Jiuqiao; Webb, Maria L.

Bioorg Med Chem Lett ; 21(6): 1871-5, 2011 Mar 15.

Artículo en Inglés | MEDLINE | ID: mdl-21353540

7.

Identification and optimization of novel 2-(4-oxo-2-aryl-quinazolin-3(4H)-yl)acetamide vasopressin V3 (V1b) receptor antagonists.

Letourneau, Jeffrey J; Riviello, Christopher M; Li, Hong; Cole, Andrew G; Ho, Koc-Kan; Zanetakos, Heather A; Desai, Hema; Zhao, Jiuqiao; Auld, Douglas S; Napier, Susan E; Thomson, Fiona J; Goan, Katharine A; Morphy, J Richard; Ohlmeyer, Michael H J; Webb, Maria L.

Bioorg Med Chem Lett ; 20(18): 5394-7, 2010 Sep 15.

Artículo en Inglés | MEDLINE | ID: mdl-20719508

8.

Variant isoforms of CD44 are P- and L-selectin ligands on colon carcinoma cells.

Hanley, William D; Napier, Susan L; Burdick, Monica M; Schnaar, Ronald L; Sackstein, Robert; Konstantopoulos, Konstantinos.

FASEB J ; 20(2): 337-9, 2006 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-16352650

9.

Quantitative trait loci for apolipoprotein B, cholesterol, and triglycerides in familial combined hyperlipidemia pedigrees.

Cantor, Rita M; de Bruin, Tjerk; Kono, Naoko; Napier, Susan; van Nas, Atila; Allayee, Hooman; Lusis, Aldons J.

Arterioscler Thromb Vasc Biol ; 24(10): 1935-41, 2004 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-15308552

10.

Selectin ligand expression regulates the initial vascular interactions of colon carcinoma cells: the roles of CD44v and alternative sialofucosylated selectin ligands.

Napier, Susan L; Healy, Zachary R; Schnaar, Ronald L; Konstantopoulos, Konstantinos.

J Biol Chem ; 282(6): 3433-41, 2007 Feb 09.

Artículo en Inglés | MEDLINE | ID: mdl-17135256

11.

Preferential binding of platelets to monocytes over neutrophils under flow.

Ahn, Kyung C; Jun, Andy J; Pawar, Parag; Jadhav, Sameer; Napier, Susan; McCarty, Owen J T; Konstantopoulos, Konstantinos.

Biochem Biophys Res Commun ; 329(1): 345-55, 2005 Apr 01.

Artículo en Inglés | MEDLINE | ID: mdl-15721313

12.

Transporters as Targets for Drugs

Napier, Susan.

Berlin, Heidelberg; Springer Berlin Heidelberg;Imprint: Springer; 2009.

Monografía en Inglés | Bibliografia | ID: bib-352265

13.

Systemic lupus erythematosus genome scan: support for linkage at 1q23, 2q33, 16q12-13, and 17q21-23 and novel evidence at 3p24, 10q23-24, 13q32, and 18q22-23.

Cantor, Rita M; Yuan, Jinying; Napier, Susan; Kono, Naoko; Grossman, Jennifer M; Hahn, Bevra H; Tsao, Betty P.

Arthritis Rheum ; 50(10): 3203-10, 2004 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-15476245

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