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1.
The atlas of RNase H antisense oligonucleotide distribution and activity in the CNS of rodents and non-human primates following central administration.
Nucleic Acids Res
; 49(2): 657-673, 2021 01 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-33367834
2.
Sequence-specific 2'-O-methoxyethyl antisense oligonucleotides activate human platelets through glycoprotein VI, triggering formation of platelet-leukocyte aggregates.
Haematologica
; 107(2): 519-531, 2022 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33567808
3.
Complement C3d/C4d Deposition on Platelets Correlates with 2'-O-Methoxyethyl Antisense Oligonucleotide-Induced Thrombocytopenia in Monkeys.
Nucleic Acid Ther
; 33(3): 209-225, 2023 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37093125
4.
Underlying Immune Disorder May Predispose Some Transthyretin Amyloidosis Subjects to Inotersen-Mediated Thrombocytopenia.
Nucleic Acid Ther
; 30(2): 94-103, 2020 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-32043907
5.
Investigation into the Mechanism(s) That Leads to Platelet Decreases in Cynomolgus Monkeys During Administration of ISIS 104838, a 2'-MOE-Modified Antisense Oligonucleotide.
Toxicol Sci
; 164(2): 613-626, 2018 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29846725
6.
Assessment of the Effects of 2'-Methoxyethyl Antisense Oligonucleotides on Platelet Count in Cynomolgus Nonhuman Primates.
Nucleic Acid Ther
; 27(4): 197-208, 2017 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-28541820
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