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1.
Combination Therapy with Gallium Protoporphyrin and Gallium Nitrate Exhibits Enhanced Antimicrobial Activity In Vitro and In Vivo against Methicillin-Resistant Staphylococcus aureus.
Mol Pharm
; 20(8): 4058-4070, 2023 08 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-37471668
2.
Synthesis and in vitro analysis of novel gallium tetrakis(4-methoxyphenyl)porphyrin and its long-acting nanoparticle as a potent antimycobacterial agent.
Bioorg Med Chem Lett
; 62: 128645, 2022 04 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-35219822
3.
Synthesis, optimization, in vitro and in vivo study of bicyclic substituted amine as MenA inhibitor.
Bioorg Med Chem Lett
; 47: 128203, 2021 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34139327
4.
Iron/Heme Metabolism-Targeted Gallium(III) Nanoparticles Are Active against Extracellular and Intracellular Pseudomonas aeruginosa and Acinetobacter baumannii.
Antimicrob Agents Chemother
; 63(4)2019 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30782994
5.
Novel MenA Inhibitors Are Bactericidal against Mycobacterium tuberculosis and Synergize with Electron Transport Chain Inhibitors.
Antimicrob Agents Chemother
; 63(6)2019 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-30962346
6.
In Vitro Efficacy of Free and Nanoparticle Formulations of Gallium(III) meso-Tetraphenylporphyrine against Mycobacterium avium and Mycobacterium abscessus and Gallium Biodistribution in Mice.
Mol Pharm
; 15(3): 1215-1225, 2018 03 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29421865
7.
Ga(III) Nanoparticles Inhibit Growth of both Mycobacterium tuberculosis and HIV and Release of Interleukin-6 (IL-6) and IL-8 in Coinfected Macrophages.
Antimicrob Agents Chemother
; 61(4)2017 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-28167548
8.
Development of potential broad spectrum antimicrobials using C2-symmetric 9-fluorenone alkyl amine.
Bioorg Med Chem Lett
; 26(8): 1997-9, 2016 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26965856
9.
Long-acting antituberculous therapeutic nanoparticles target macrophage endosomes.
FASEB J
; 28(12): 5071-82, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25122556
10.
Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages.
J Immunol
; 189(2): 744-54, 2012 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22711894
11.
Synthesis of azide derivative and discovery of glyoxalase pathway inhibitor against pathogenic bacteria.
Bioorg Med Chem Lett
; 23(22): 6138-40, 2013 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24076169
12.
In Vitro and In Vivo Antimicrobial Activity of an Oxidative Stress-Mediated Bicyclic Menaquinone Biosynthesis Inhibitor against MRSA.
ACS Infect Dis
; 9(10): 2016-2024, 2023 Oct 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-37655755
13.
Investigating Novel IspE Inhibitors of the MEP Pathway in Mycobacterium.
Microorganisms
; 12(1)2023 Dec 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-38276186
14.
Development of Gallium(III) as an Antimicrobial Drug Targeting Pathophysiologic Iron Metabolism of Human Pathogens.
ACS Infect Dis
; 9(4): 716-738, 2023 04 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-36995299
15.
Effect of Cannabidiol on the Neural Glyoxalase Pathway Function and Longevity of Several C. elegans Strains Including a C. elegans Alzheimer's Disease Model.
ACS Chem Neurosci
; 13(8): 1165-1177, 2022 04 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-35385645
16.
Combining Gallium Protoporphyrin and Gallium Nitrate Enhances In Vitro and In Vivo Efficacy against Pseudomonas aeruginosa: Role of Inhibition of Bacterial Antioxidant Enzymes and Resultant Increase in Cytotoxic Reactive Oxygen Species.
ACS Infect Dis
; 8(10): 2096-2105, 2022 10 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-36049087
17.
Nanoparticulate ß-Cyclodextrin with Gallium Tetraphenylporphyrin Demonstrates in Vitro and in Vivo Antimicrobial Efficacy against Mycobacteroides abscessus and Mycobacterium avium.
ACS Infect Dis
; 7(8): 2299-2309, 2021 08 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-34314150
18.
DosS responds to a reduced electron transport system to induce the Mycobacterium tuberculosis DosR regulon.
J Bacteriol
; 192(24): 6447-55, 2010 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-20952575
19.
Menaquinone synthesis is critical for maintaining mycobacterial viability during exponential growth and recovery from non-replicating persistence.
Mol Microbiol
; 72(1): 85-97, 2009 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-19220750
20.
Neural Glyoxalase Pathway Enhancement by Morin Derivatives in an Alzheimer's Disease Model.
ACS Chem Neurosci
; 11(3): 356-366, 2020 02 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-31909963