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1.
Btk inhibition suppresses agonist-induced human macrophage activation and inflammatory gene expression in RA synovial tissue explants.
Ann Rheum Dis
; 74(8): 1603-11, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-24764451
2.
Natural regulatory T cells are resistant to calcium release-activated calcium (CRAC/ORAI) channel inhibition.
Int Immunol
; 25(9): 497-506, 2013 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-23667148
3.
Suppression of glomerulonephritis in lupus-prone NZB × NZW mice by RN486, a selective inhibitor of Bruton's tyrosine kinase.
Arthritis Rheum
; 65(9): 2380-91, 2013 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-23754328
4.
Thymic stromal lymphopoietin receptor blockade reduces allergic inflammation in a cynomolgus monkey model of asthma.
J Allergy Clin Immunol
; 132(2): 455-62, 2013 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-23810153
5.
RN486, a selective Bruton's tyrosine kinase inhibitor, abrogates immune hypersensitivity responses and arthritis in rodents.
J Pharmacol Exp Ther
; 341(1): 90-103, 2012 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-22228807
6.
Inhibition of IRF5 cellular activity with cell-penetrating peptides that target homodimerization.
Sci Adv
; 6(20): eaay1057, 2020 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-32440537
7.
Bruton's Tyrosine Kinase mediates platelet receptor-induced generation of microparticles: a potential mechanism for amplification of inflammatory responses in rheumatoid arthritis synovial joints.
Immunol Lett
; 150(1-2): 97-104, 2013 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-23266841
8.
Development of a pharmacodynamic assay based on PLCγ2 phosphorylation for quantifying spleen tyrosine kinase (SYK)-Bruton's tyrosine kinase (BTK) signaling.
J Biomol Screen
; 18(8): 890-8, 2013 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-23704133
9.
Selective inhibition of spleen tyrosine kinase (SYK) with a novel orally bioavailable small molecule inhibitor, RO9021, impinges on various innate and adaptive immune responses: implications for SYK inhibitors in autoimmune disease therapy.
Arthritis Res Ther
; 15(5): R146, 2013 Oct 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-24286216
10.
Characterization of a novel CRAC inhibitor that potently blocks human T cell activation and effector functions.
Mol Immunol
; 54(3-4): 355-67, 2013 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-23357789
11.
A novel cannabinoid peripheral cannabinoid receptor-selective inverse agonist blocks leukocyte recruitment in vivo.
J Pharmacol Exp Ther
; 316(2): 780-8, 2006 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-16258021
12.
Characterization of peripheral human cannabinoid receptor (hCB2) expression and pharmacology using a novel radioligand, [35S]Sch225336.
J Biol Chem
; 281(38): 28143-51, 2006 Sep 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-16754676
13.
Triaryl bis-sulfones as a new class of cannabinoid CB2 receptor inhibitors: identification of a lead and initial SAR studies.
Bioorg Med Chem Lett
; 15(3): 783-6, 2005 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-15664857
14.
Inhibition of the development of collagen-induced arthritis in rhesus monkeys by a small molecular weight antagonist of CCR5.
Arthritis Rheum
; 52(2): 627-36, 2005 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-15693002
15.
The pyrimidinergic P2Y6 receptor mediates a novel release of proinflammatory cytokines and chemokines in monocytic cells stimulated with UDP.
Biochem Biophys Res Commun
; 330(2): 467-73, 2005 May 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-15796906
16.
Blocking ion channel KCNN4 alleviates the symptoms of experimental autoimmune encephalomyelitis in mice.
Eur J Immunol
; 35(4): 1027-36, 2005 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-15770697
17.
Inhibition of fucosyltransferase VII by gallic acid and its derivatives.
Arch Biochem Biophys
; 425(1): 51-7, 2004 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-15081893
18.
Growth and expansion of human T regulatory type 1 cells are independent from TCR activation but require exogenous cytokines.
Eur J Immunol
; 32(8): 2237-45, 2002 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-12209636
19.
Interleukin-17 promotes angiogenesis and tumor growth.
Blood
; 101(7): 2620-7, 2003 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-12411307
20.
IL-10 and TGF-beta induce alloreactive CD4+CD25- T cells to acquire regulatory cell function.
Blood
; 101(12): 5076-83, 2003 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-12609834