Detalles de la búsqueda
1.
MEDI3039, a novel highly potent tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 2 agonist, causes regression of orthotopic tumors and inhibits outgrowth of metastatic triple-negative breast cancer.
Breast Cancer Res
; 21(1): 27, 2019 02 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-30777098
2.
Preclinical development of a high affinity α-synuclein antibody, MEDI1341, that can enter the brain, sequester extracellular α-synuclein and attenuate α-synuclein spreading in vivo.
Neurobiol Dis
; 132: 104582, 2019 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31445162
3.
Detecting bliss synergy in in vivo combination studies with a tumor kinetic model.
Pharm Stat
; 18(6): 688-699, 2019 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-31140720
4.
Phase II study of MEDI-575, an anti-platelet-derived growth factor-α antibody, in patients with recurrent glioblastoma.
J Neurooncol
; 131(1): 185-191, 2017 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27844311
5.
Safety and antitumour activity of durvalumab plus tremelimumab in non-small cell lung cancer: a multicentre, phase 1b study.
Lancet Oncol
; 17(3): 299-308, 2016 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-26858122
6.
Sustained peripheral depletion of amyloid-ß with a novel form of neprilysin does not affect central levels of amyloid-ß.
Brain
; 137(Pt 2): 553-64, 2014 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-24259408
7.
Combinatorial approaches for controlling pericarp browning in Litchi (Litchi chinensis) fruit.
J Food Sci Technol
; 52(9): 5418-26, 2015 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-26344958
8.
National, regional, and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: a systematic analysis and implications.
Lancet
; 379(9832): 2162-72, 2012 Jun 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-22682464
9.
Preterm birth-associated neurodevelopmental impairment estimates at regional and global levels for 2010.
Pediatr Res
; 74 Suppl 1: 17-34, 2013 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-24366461
10.
A QSP Model for Predicting Clinical Responses to Monotherapy, Combination and Sequential Therapy Following CTLA-4, PD-1, and PD-L1 Checkpoint Blockade.
Sci Rep
; 9(1): 11286, 2019 08 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31375756
11.
Exposure-Response Analysis of Overall Survival for Tremelimumab in Unresectable Malignant Mesothelioma: The Confounding Effect of Disease Status.
Clin Transl Sci
; 12(5): 450-458, 2019 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-30883000
12.
A Computational Model of Neoadjuvant PD-1 Inhibition in Non-Small Cell Lung Cancer.
AAPS J
; 21(5): 79, 2019 06 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-31236847
13.
Nullifying phosphatidic acid effect and controlling phospholipase D associated browning in litchi pericarp through combinatorial application of hexanal and inositol.
Sci Rep
; 9(1): 2402, 2019 02 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-30787348
14.
In silico simulation of a clinical trial with anti-CTLA-4 and anti-PD-L1 immunotherapies in metastatic breast cancer using a systems pharmacology model.
R Soc Open Sci
; 6(5): 190366, 2019 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-31218069
15.
Prognostic Significance of Liver Metastasis in Durvalumab-Treated Lung Cancer Patients.
Clin Lung Cancer
; 20(6): e601-e608, 2019 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-31327642
16.
Clinical Activity, Tolerability, and Long-Term Follow-Up of Durvalumab in Patients With Advanced NSCLC.
J Thorac Oncol
; 14(10): 1794-1806, 2019 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31228626
17.
Sustainable Development Goals: Leveraging the Global Agenda for Driving Health Policy Reforms and Achieving Universal Health Coverage in India.
Indian J Community Med
; 43(4): 255-259, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-30662175
18.
Population Modeling of Tumor Kinetics and Overall Survival to Identify Prognostic and Predictive Biomarkers of Efficacy for Durvalumab in Patients With Urothelial Carcinoma.
Clin Pharmacol Ther
; 103(4): 643-652, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29243222
19.
Population Pharmacokinetics of Durvalumab in Cancer Patients and Association With Longitudinal Biomarkers of Disease Status.
Clin Pharmacol Ther
; 103(4): 631-642, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29243223
20.
A computational multiscale agent-based model for simulating spatio-temporal tumour immune response to PD1 and PDL1 inhibition.
J R Soc Interface
; 14(134)2017 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28931635