Detalles de la búsqueda
1.
Mineralocorticoid and glucocorticoid receptors differentially regulate NF-kappaB activity and pro-inflammatory cytokine production in murine BV-2 microglial cells.
J Neuroinflammation
; 9: 260, 2012 Nov 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-23190711
2.
Direct protein-protein interaction of 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase in the endoplasmic reticulum lumen.
Biochim Biophys Acta
; 1783(8): 1536-43, 2008 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-18381077
3.
Hexose-6-phosphate dehydrogenase modulates the effect of inhibitors and alternative substrates of 11beta-hydroxysteroid dehydrogenase 1.
Mol Cell Endocrinol
; 301(1-2): 117-22, 2009 Mar 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-19010388
4.
11beta-Hydroxysteroid dehydrogenase 1 reductase activity is dependent on a high ratio of NADPH/NADP(+) and is stimulated by extracellular glucose.
Mol Cell Endocrinol
; 301(1-2): 137-41, 2009 Mar 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-18778749
5.
Coffee inhibits the reactivation of glucocorticoids by 11beta-hydroxysteroid dehydrogenase type 1: a glucocorticoid connection in the anti-diabetic action of coffee?
FEBS Lett
; 580(17): 4081-5, 2006 Jul 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-16814782
6.
The discovery of new 11beta-hydroxysteroid dehydrogenase type 1 inhibitors by common feature pharmacophore modeling and virtual screening.
J Med Chem
; 49(12): 3454-66, 2006 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-16759088
7.
Why is 11beta-hydroxysteroid dehydrogenase type 1 facing the endoplasmic reticulum lumen? Physiological relevance of the membrane topology of 11beta-HSD1.
Mol Cell Endocrinol
; 248(1-2): 15-23, 2006 Mar 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-16412558
8.
Role of Pro-637 and Gln-642 in human glucocorticoid receptors and Ser-843 and Leu-848 in mineralocorticoid receptors in their differential responses to cortisol and aldosterone.
J Steroid Biochem Mol Biol
; 159: 31-40, 2016 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-26907965
9.
Organotins disrupt the 11beta-hydroxysteroid dehydrogenase type 2-dependent local inactivation of glucocorticoids.
Environ Health Perspect
; 113(11): 1600-6, 2005 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-16263518
10.
Hexose-6-phosphate dehydrogenase determines the reaction direction of 11beta-hydroxysteroid dehydrogenase type 1 as an oxoreductase.
FEBS Lett
; 571(1-3): 129-33, 2004 Jul 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-15280030
11.
Pharmacophore Model Refinement for 11ß-Hydroxysteroid Dehydrogenase Inhibitors: Search for Modulators of Intracellular Glucocorticoid Concentrations.
Mol Inform
; 33(1): 15-25, 2014 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-27485195
12.
The microsomal enzyme 17ß-hydroxysteroid dehydrogenase 3 faces the cytoplasm and uses NADPH generated by glucose-6-phosphate dehydrogenase.
Endocrinology
; 154(1): 205-13, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23183177
13.
Cysteine-10 on 17 ß -Hydroxysteroid Dehydrogenase 1 Has Stabilizing Interactions in the Cofactor Binding Region and Renders Sensitivity to Sulfhydryl Modifying Chemicals.
Int J Cell Biol
; 2013: 769536, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-24348564
14.
Virtual screening as a strategy for the identification of xenobiotics disrupting corticosteroid action.
PLoS One
; 7(10): e46958, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-23056542
15.
The glucocorticoid-activating enzyme 11beta-hydroxysteroid dehydrogenase type 1 has broad substrate specificity: Physiological and toxicological considerations.
J Steroid Biochem Mol Biol
; 119(1-2): 1-13, 2010 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-20100573
16.
The UV-filter benzophenone-1 inhibits 17beta-hydroxysteroid dehydrogenase type 3: Virtual screening as a strategy to identify potential endocrine disrupting chemicals.
Biochem Pharmacol
; 79(8): 1189-99, 2010 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20005209
17.
Discovery of nonsteroidal 17beta-hydroxysteroid dehydrogenase 1 inhibitors by pharmacophore-based screening of virtual compound libraries.
J Med Chem
; 51(14): 4188-99, 2008 Jul 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-18533708
18.
Hexose-6-phosphate dehydrogenase modulates 11beta-hydroxysteroid dehydrogenase type 1-dependent metabolism of 7-keto- and 7beta-hydroxy-neurosteroids.
PLoS One
; 2(6): e561, 2007 Jun 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-17593962
19.
Impaired protein stability of 11beta-hydroxysteroid dehydrogenase type 2: a novel mechanism of apparent mineralocorticoid excess.
J Am Soc Nephrol
; 18(4): 1262-70, 2007 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-17314322
20.
PhenomicDB: a multi-species genotype/phenotype database for comparative phenomics.
Bioinformatics
; 21(3): 418-20, 2005 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-15374875
Resultados
1 -
20
de 20
1
Próxima >
>>