Detalles de la búsqueda
1.
Bayesian methods for the design and analysis of noninferiority trials.
J Biopharm Stat
; 26(5): 823-41, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-26247350
2.
Estimation of the inter- and intrasubject variability of the diurnal serum cortisol rhythm in healthy male subjects to evaluate the biomarker potential for drug target engagement.
Int J Clin Pharmacol Ther
; 53(3): 199-205, 2015 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-25546161
3.
Modeling and simulations to confirm a controlled hypoglycemic stress test in healthy subjects is not associated with clinically significant QT prolongations.
Int J Clin Pharmacol Ther
; 52(9): 717-25, 2014 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-24887333
4.
The current state of Bayesian methods in medical product development: survey results and recommendations from the DIA Bayesian Scientific Working Group.
Pharm Stat
; 13(1): 3-12, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24027093
5.
Bayesian sample size determination for a clinical trial with correlated continuous and binary outcomes.
J Biopharm Stat
; 23(4): 790-803, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23786161
6.
Design and Execution of Sustainable Decentralized Clinical Trials.
Clin Pharmacol Ther
; 114(4): 802-809, 2023 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-37489911
7.
Why are not There More Bayesian Clinical Trials? Perceived Barriers and Educational Preferences Among Medical Researchers Involved in Drug Development.
Ther Innov Regul Sci
; 57(3): 417-425, 2023 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34978048
8.
Why are There not More Bayesian Clinical Trials? Ability to Interpret Bayesian and Conventional Statistics Among Medical Researchers.
Ther Innov Regul Sci
; 57(3): 426-435, 2023 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36496452
9.
Decision making in clinical trials: Interim analyses, innovative design, and biomarkers.
Alzheimers Dement (N Y)
; 9(4): e12421, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37867532
10.
Pharmacokinetics and pharmacodynamics following maintenance doses of prasugrel and clopidogrel in Chinese carriers of CYP2C19 variants.
Br J Clin Pharmacol
; 73(1): 93-105, 2012 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-21689142
11.
Donanemab (LY3002813) dose-escalation study in Alzheimer's disease.
Alzheimers Dement (N Y)
; 7(1): e12112, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-33614890
12.
Phase II (NAVIGATE-AD study) Results of LY3202626 Effects on Patients with Mild Alzheimer's Disease Dementia.
J Alzheimers Dis Rep
; 5(1): 321-336, 2021 Apr 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-34113788
13.
Tadalafil is efficacious and well tolerated in the treatment of erectile dysfunction (ED) in men over 65 years of age: results from Multiple Observations in Men with ED in National Tadalafil Study in the United States.
J Sex Med
; 5(3): 716-25, 2008 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-18304286
14.
First-line treatment of patients with advanced or metastatic squamous non-small cell lung cancer: systematic review and network meta-analysis.
J Thorac Dis
; 10(12): 6677-6694, 2018 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-30746213
15.
Advancing innovative clinical trials to efficiently deliver medicines to patients.
Nat Rev Drug Discov
; 21(8): 543-544, 2022 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35760887
16.
Study protocol: systematic review and meta-analysis of randomized controlled trials in first-line treatment of squamous non-small cell lung cancer.
Syst Rev
; 3: 102, 2014 Sep 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-25227571
17.
Effects of a novel mGlu2/3 receptor agonist prodrug, LY2140023 monohydrate, on central monoamine turnover as determined in human and rat cerebrospinal fluid.
Psychopharmacology (Berl)
; 219(4): 959-70, 2012 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-21847569
18.
Pharmacodynamics and pharmacokinetics of single doses of prasugrel 30 mg and clopidogrel 300 mg in healthy Chinese and white volunteers: an open-label trial.
Clin Ther
; 32(2): 365-79, 2010 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-20206794
19.
Efficacy and safety of tadalafil in men with erectile dysfunction with a high prevalence of comorbid conditions: results from MOMENTUS: multiple observations in men with erectile dysfunction in National Tadalafil Study in the US.
J Sex Med
; 4(1): 166-175, 2007 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-17233782
20.
Efficacy and safety of tadalafil across ethnic groups and various risk factors in men with erectile dysfunction: Use of a novel noninferiority study design.
J Sex Med
; 3(3): 492-503, 2006 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-16681475