Detalles de la búsqueda
1.
Structure-activity-relationship studies on dihydrofuran-fused perhydrophenanthrenes as an anti-Alzheimer's disease agent.
Bioorg Med Chem
; 21(15): 4459-71, 2013 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23806833
2.
Synthesis of dihydrofuran-fused perhydrophenanthrenes having a phenolic hydroxyl group as a novel anti-Alzheimer's disease agent.
Bioorg Med Chem Lett
; 22(1): 449-52, 2012 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22142544
3.
Synthesis and biological evaluation of pyrethroid insecticide-derivatives as a chemical inducer for Bdnf mRNA expression in neurons.
Bioorg Med Chem
; 20(8): 2564-71, 2012 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22429507
4.
Synthesis and anti-influenza virus activity of dihydrofuran-fused perhydrophenanthrenes with a benzyloxy-type side-chain.
Bioorg Med Chem
; 18(4): 1477-81, 2010 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20097080
5.
Treatment with SRT1720, a SIRT1 activator, ameliorates fatty liver with reduced expression of lipogenic enzymes in MSG mice.
Am J Physiol Endocrinol Metab
; 297(5): E1179-86, 2009 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-19724016
6.
Design, synthesis, and biological evaluation of artificial macrosphelides in the search for new apoptosis-inducing agents.
Chemistry
; 15(23): 5799-813, 2009 Jun 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-19370747
7.
Efficient enantio- and diastereodivergent synthesis of poison-frog alkaloids 251O and trans-223B.
J Org Chem
; 74(17): 6784-91, 2009 Sep 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-19637860
8.
Enhancement of hyperthermia-induced apoptosis by a new synthesized class of benzocycloalkene compounds.
Apoptosis
; 13(3): 448-61, 2008 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-18224486
9.
Rapid and transient intracellular oxidative stress due to novel macrosphelides trigger apoptosis via Fas/caspase-8-dependent pathway in human lymphoma U937 cells.
Chem Biol Interact
; 170(2): 86-99, 2007 Nov 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-17727829
10.
Flexible synthetic routes to poison-frog alkaloids of the 5,8-disubstituted indolizidine-class I: synthesis of common lactam chiral building blocks and application to the synthesis of (-)-203A, (-)-205A, and (-)-219F.
Beilstein J Org Chem
; 3: 29, 2007 Sep 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-17903239
11.
Flexible synthesis of poison-frog alkaloids of the 5,8-disubstituted indolizidine-class. II: Synthesis of (-)-209B, (-)-231C, (-)-233D, (-)-235B", (-)-221I, and an epimer of 193E and pharmacological effects at neuronal nicotinic acetylcholine receptors.
Beilstein J Org Chem
; 3: 30, 2007.
Artículo
en Inglés
| MEDLINE | ID: mdl-21931443
12.
Synthesis of macrosphelides with a thiazole side chain: new antitumor candidates having apoptosis-inducing property.
Org Lett
; 8(20): 4609-12, 2006 Sep 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-16986962
13.
Novel phorbol esters exert dichotomous effects on inhibition of HIV-1 infection and activation of latent HIV-1 expression.
Antivir Chem Chemother
; 16(5): 303-13, 2005.
Artículo
en Inglés
| MEDLINE | ID: mdl-16245646
14.
New strategy for the total synthesis of macrosphelides a and B based on ring-closing metathesis.
Org Lett
; 5(16): 2939-41, 2003 Aug 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-12889913
15.
Concise and highly stereocontrolled synthesis of 1-deoxygalactonojirimycin and its congeners using dioxanylpiperidene, a promising chiral building block.
Org Lett
; 5(14): 2527-9, 2003 Jul 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-12841772
16.
A novel C(2)-symmetric 2,6-diallylpiperidine carboxylic acid methyl ester as a promising chiral building block for piperidine-related alkaloids.
Org Lett
; 4(20): 3459-62, 2002 Oct 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-12323043
17.
Synthesis of alkaloid 223A and a structural revision.
Org Lett
; 4(10): 1715-7, 2002 May 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-12000281
18.
Efficient approach to 1,2-diazepines via formal diazomethylene insertion into the C-C bond of cyclobutenones.
Org Lett
; 14(13): 3510-3, 2012 Jul 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-22721410
19.
Total synthesis of the antipode of alkaloid 205 B.
Angew Chem Int Ed Engl
; 42(32): 3808-10, 2003 Aug 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-12923851
20.
Mechanism of apoptosis induced by a newly synthesized derivative of macrosphelides with a thiazole side chain.
Chem Biol Interact
; 177(3): 218-26, 2009 Feb 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-19014919