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1.
Pleckstrin homology domain leucine-rich repeat protein phosphatases set the amplitude of receptor tyrosine kinase output.
Proc Natl Acad Sci U S A
; 111(38): E3957-65, 2014 Sep 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-25201979
2.
DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance.
Nat Commun
; 15(1): 275, 2024 Jan 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-38177131
3.
Disruption of the interface between the pleckstrin homology (PH) and kinase domains of Akt protein is sufficient for hydrophobic motif site phosphorylation in the absence of mTORC2.
J Biol Chem
; 286(45): 39122-9, 2011 Nov 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-21908613
4.
Mislocalization of the E3 ligase, ß-transducin repeat-containing protein 1 (ß-TrCP1), in glioblastoma uncouples negative feedback between the pleckstrin homology domain leucine-rich repeat protein phosphatase 1 (PHLPP1) and Akt.
J Biol Chem
; 286(22): 19777-88, 2011 Jun 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-21454620
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