Detalles de la búsqueda
1.
Molecular determinants of subtype-selective efficacies of cytisine and the novel compound NS3861 at heteromeric nicotinic acetylcholine receptors.
J Biol Chem
; 288(4): 2559-70, 2013 Jan 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-23229547
2.
In vitro pharmacological characterization of a novel selective alpha7 neuronal nicotinic acetylcholine receptor agonist ABT-107.
J Pharmacol Exp Ther
; 334(3): 863-74, 2010 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20504915
3.
The novel compound (+/-)-1-[10-((E)-3-Phenyl-allyl)-3,10-diaza-bicyclo[4.3.1]dec-3-yl]-propan-1-one (NS7051) attenuates nociceptive transmission in animal models of experimental pain; a pharmacological comparison with the combined mu-opioid receptor agonist and monoamine reuptake inhibitor tramadol.
Neuropharmacology
; 54(2): 331-43, 2008 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-18037451
4.
Insensitivity of NMRI mice to selective serotonin reuptake inhibitors in the tail suspension test can be reversed by co-treatment with 5-hydroxytryptophan.
Psychopharmacology (Berl)
; 199(2): 137-50, 2008 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-18496675
5.
The nicotinic alpha7 acetylcholine receptor agonist ssr180711 is unable to activate limbic neurons in mice overexpressing human amyloid-beta1-42.
Brain Res
; 1227: 240-7, 2008 Aug 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-18619425
6.
Engineered α4ß2 nicotinic acetylcholine receptors as models for measuring agonist binding and effect at the orthosteric low-affinity α4-α4 interface.
Neuropharmacology
; 92: 135-45, 2015 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-25595102
7.
Bioisosteric modifications of 2-arylureidobenzoic acids: selective noncompetitive antagonists for the homomeric kainate receptor subtype GluR5.
J Med Chem
; 47(27): 6948-57, 2004 Dec 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-15615543
8.
2-arylureidobenzoic acids: selective noncompetitive antagonists for the homomeric kainate receptor subtype GluR5.
J Med Chem
; 46(26): 5834-43, 2003 Dec 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-14667236
9.
[11C]NS8880, a promising PET radiotracer targeting the norepinephrine transporter.
Nucl Med Biol
; 41(9): 758-64, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-25127515
10.
A combined α7 nicotinic acetylcholine receptor agonist and monoamine reuptake inhibitor, NS9775, represents a novel profile with potential benefits in emotional and cognitive disturbances.
Neuropharmacology
; 73: 183-91, 2013 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-23748055
11.
Synthesis, pharmacology, and biostructural characterization of novel α4ß2 nicotinic acetylcholine receptor agonists.
J Med Chem
; 56(3): 940-51, 2013 Feb 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-23256554
12.
Combined α7 nicotinic acetylcholine receptor agonism and partial serotonin transporter inhibition produce antidepressant-like effects in the mouse forced swim and tail suspension tests: a comparison of SSR180711 and PNU-282987.
Pharmacol Biochem Behav
; 100(3): 624-9, 2012 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-22108649
13.
Crystal structure of Lymnaea stagnalis AChBP complexed with the potent nAChR antagonist DHßE suggests a unique mode of antagonism.
PLoS One
; 7(8): e40757, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22927902
14.
GABA(A) receptor α subunits differentially contribute to diazepam tolerance after chronic treatment.
PLoS One
; 7(8): e43054, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22912786
15.
CyPPA, a Positive SK3/SK2 Modulator, Reduces Activity of Dopaminergic Neurons, Inhibits Dopamine Release, and Counteracts Hyperdopaminergic Behaviors Induced by Methylphenidate.
Front Pharmacol
; 3: 11, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22347859
16.
Subtype-selective nicotinic acetylcholine receptor agonists enhance the responsiveness to citalopram and reboxetine in the mouse forced swim test.
J Psychopharmacol
; 25(10): 1347-56, 2011 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-20360159
17.
11C-NS14492 as a novel PET radioligand for imaging cerebral alpha7 nicotinic acetylcholine receptors: in vivo evaluation and drug occupancy measurements.
J Nucl Med
; 52(9): 1449-56, 2011 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-21828113
18.
The dopaminergic stabilizers pridopidine (ACR16) and (-)-OSU6162 display dopamine D(2) receptor antagonism and fast receptor dissociation properties.
Eur J Pharmacol
; 628(1-3): 19-26, 2010 Feb 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-19919834
19.
The rapid hydrolysis of chlordiazepoxide to demoxepam may affect the outcome of chronic osmotic minipump studies.
Psychopharmacology (Berl)
; 208(4): 555-62, 2010 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-20066402
20.
Chronic oral nicotine increases brain [3H]epibatidine binding and responsiveness to antidepressant drugs, but not nicotine, in the mouse forced swim test.
Psychopharmacology (Berl)
; 205(3): 517-28, 2009 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-19452140